与肾移植存活相关的高分子量淋巴细胞Fcγ受体阻断因子的分离与鉴定
Isolation and characterization of a high molecular weight lymphocyte Fc gamma receptor-blocking factor associated with renal allograft survival.
作者信息
Sandilands G P, Cocker J E, McMillan M A, Owsianka A M, Marsden H, Junor B J, Briggs J D, MacSween R N
机构信息
University Department of Pathology, Western Infirmary, Glasgow, Scotland.
出版信息
Clin Exp Immunol. 1990 Oct;82(1):140-4. doi: 10.1111/j.1365-2249.1990.tb05417.x.
We have confirmed our previous observation that improved human renal allograft survival is associated with the presence in pre-transplant serum of a high molecular weight lymphocyte Fc gamma receptor-blocking factor. Serum fractionation studies suggest that this factor is a complex protein consisting of IgG together with an IgG-binding protein which has an apparent molecular weight of approximately 60 kD.
我们已证实了我们之前的观察结果，即人类肾移植存活率的提高与移植前血清中存在的高分子量淋巴细胞Fcγ受体阻断因子有关。血清分级分离研究表明，该因子是一种复合蛋白，由IgG和一种表观分子量约为60 kD的IgG结合蛋白组成。
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