Dupuy C, Periquet G, Serbielle C, Bézier A, Louis F, Drezen J-M
Institut de Recherche sur la Biologie de l'Insecte, UMR CNRS 6035, Université F. Rabelais, UFR Sciences et Techniques, Parc Grandmont, 37200 Tours, France.
Genetica. 2011 Apr;139(4):489-96. doi: 10.1007/s10709-011-9569-x. Epub 2011 Mar 31.
Bracoviruses are used by parasitoid wasps to allow development of their progeny within the body of lepidopteran hosts. In parasitoid wasps, the bracovirus exists as a provirus, integrated in a wasp chromosome. Viral replication occurs in wasp ovaries and leads to formation of particles containing dsDNA circles (segments) that are injected into the host body during wasp oviposition. We identified a large DNA transposon Maverick in a parasitoid wasp bracovirus. Closely related elements are present in parasitoid wasp genomes indicating that the element in CcBV corresponds to the insertion of an endogenous wasp Maverick in CcBV provirus. The presence of the Maverick in a bracovirus genome suggests the possibility of transposon transfers from parasitoids to lepidoptera via bracoviruses.
杆状病毒被寄生蜂用来使其后代在鳞翅目宿主的体内发育。在寄生蜂中，杆状病毒以原病毒的形式存在，整合在黄蜂染色体中。病毒复制发生在黄蜂卵巢中，并导致形成含有双链DNA环（片段）的颗粒，这些颗粒在黄蜂产卵时被注入宿主体内。我们在一种寄生蜂杆状病毒中鉴定出一个大型DNA转座子Maverick。在寄生蜂基因组中存在密切相关的元件，这表明CcBV中的元件对应于内源性黄蜂Maverick插入到CcBV原病毒中。杆状病毒基因组中Maverick的存在表明转座子有可能通过杆状病毒从寄生蜂转移到鳞翅目昆虫中。
