Coryell W
University of Iowa, Department of Psychiatry, Iowa City 52242.
J Affect Disord. 1990 Jul;19(3):163-9. doi: 10.1016/0165-0327(90)90086-n.
Seventy-six inpatients with major depression received a 1-mg dexamethasone suppression test (DST) and began a semi-annual follow-up lasting 5 years. The 20 subjects with abnormal baseline DST results were significantly more likely to make psychologically serious suicide attempts during follow-up though baseline suppressors were as likely as non-suppressors to make non-serious attempts. Patients who were non-suppressors at the beginning of follow-up were also more likely to develop'mania or hypomania, whether or not they had a bipolar diagnosis at intake.
76名重度抑郁症住院患者接受了1毫克地塞米松抑制试验（DST），并开始了为期5年的半年一次随访。20名基线DST结果异常的受试者在随访期间进行心理上严重自杀企图的可能性显著更高，尽管基线抑制者与非抑制者进行非严重自杀企图的可能性相同。随访开始时为非抑制者的患者，无论入院时是否被诊断为双相情感障碍，也更有可能发展为“躁狂或轻躁狂”。
