Substance Misuse Directorate, Royal Edinburgh Hospital, UK. indranisb @ doctors.org.uk
Eur Addict Res. 2011;17(4):169-71. doi: 10.1159/000324343. Epub 2011 Apr 1.
γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man who was admitted for detoxification from GBL. He reported having sourced the GBL by diluting the contents of nail varnish remover pads with water. During his admission he developed a severe withdrawal delirium and acute renal failure. He required admission to the intensive care unit. Physicians and psychiatrists should be aware of toxic sources of GBL leading to renal failure and consider GBL in those presenting with agitation, psychosis or coma.
γ-丁内酯（GBL）是一种常见的滥用药物，在互联网上很容易获得。2010 年 1 月，英国将其分类为 C 类药物后，互联网供应变得困难。一些人因此从工业溶剂中获取 GBL。我们报告了一例 24 岁男性，因 GBL 戒断而入院。他报告说，他通过用水稀释指甲油去除垫的内容物来获取 GBL。在住院期间，他出现了严重的戒断谵妄和急性肾衰竭。他需要入住重症监护病房。医生和精神科医生应该意识到导致肾衰竭的 GBL 的有毒来源，并考虑那些出现激越、精神病或昏迷的患者是否有 GBL 摄入。
