South Essex Partnership University Foundation Trust, Calnwood Court, Luton, Bedfordshire, UK.
Psychiatr Danub. 2011 Sep;23 Suppl 1:S32-4.
GBL (gamma-butyro-lactone) is converted to Gamma hydroxyl butyrate (GHB) in the body. GBL and GHB are available in liquid form and powder form. Once categorised under "legal highs", these two are not associated with any dependence or withdrawal in animal studies. But there are case reports indicating their high dependence potential in humans. We here present a case of a 29 year old who came to the attention of psychiatric services with very bizarre presentation and needed a host of investigations and expert views from various medical disciplines. He was treated mainly symptomatically followed by a sudden dramatic recovery on the 11th day after presentation. GBL is getting popular as a recreational drug and its withdrawal should be seriously considered in the list of medical causes leading to Delirium.
GBL（γ-丁内酯）在体内转化为 GHB（γ-羟基丁酸）。GBL 和 GHB 有液体和粉末两种形式。这两种物质曾被归类为“合法兴奋剂”，在动物研究中与任何依赖或戒断无关。但有病例报告表明它们在人类身上具有很高的依赖潜力。我们在此报告一例 29 岁男性，因非常奇特的表现引起精神科注意，需要进行大量的检查，并征求各医学专业的专家意见。他主要接受对症治疗，在出现症状后的第 11 天突然戏剧性地康复。GBL 作为一种娱乐性药物越来越流行，其戒断应被认真考虑在导致谵妄的医学病因列表中。
