• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Evidence for successful implementation of exposure and response prevention in a naturalistic group format for pediatric OCD.暴露和反应预防在自然群体格式中成功实施治疗儿科 OCD 的证据。
Depress Anxiety. 2011 Apr;28(4):342-8. doi: 10.1002/da.20789. Epub 2011 Feb 24.
2
[Effectiveness of cognitive-behavioral therapy in children and adolescents with obsessive-compulsive disorders treated in an outpatient clinic].[认知行为疗法对门诊治疗的儿童和青少年强迫症患者的疗效]
Z Kinder Jugendpsychiatr Psychother. 2017;45(3):219-235. doi: 10.1024/1422-4917/a000416. Epub 2016 Apr 8.
3
A naturalistic exploratory study of the impact of demographic, phenotypic and comorbid features in pediatric obsessive-compulsive disorder.一项关于人口统计学、表型和共病特征对儿科强迫症影响的自然主义探索性研究。
Psychopathology. 2010;43(2):69-78. doi: 10.1159/000274175. Epub 2010 Jan 9.
4
Does the addition of cognitive therapy to exposure and response prevention for obsessive compulsive disorder enhance clinical efficacy? A randomized controlled trial in a community setting.认知疗法联合暴露反应预防治疗强迫症是否能增强临床疗效?一项社区环境下的随机对照试验。
Br J Clin Psychol. 2019 Mar;58(1):1-18. doi: 10.1111/bjc.12188. Epub 2018 Jul 8.
5
Sleep-Related Problems in Pediatric Obsessive-Compulsive Disorder and Intensive Exposure Therapy.儿童强迫症的睡眠相关问题与密集暴露疗法
Behav Ther. 2019 May;50(3):608-620. doi: 10.1016/j.beth.2018.09.008. Epub 2018 Sep 28.
6
Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder: A Randomized Clinical Trial.D-环丝氨酸对集中暴露和反应预防治疗难治性强迫症效果的影响:一项随机临床试验。
JAMA Netw Open. 2020 Aug 3;3(8):e2013249. doi: 10.1001/jamanetworkopen.2020.13249.
7
Exposure and response prevention process predicts treatment outcome in youth with OCD.暴露与反应阻止疗法过程可预测患有强迫症的青少年的治疗结果。
J Abnorm Child Psychol. 2015 Apr;43(3):543-52. doi: 10.1007/s10802-014-9917-2.
8
Clinical predictors of long-term outcome in obsessive-compulsive disorder.强迫症长期预后的临床预测因素。
Depress Anxiety. 2013 Aug;30(8):763-72. doi: 10.1002/da.22013. Epub 2012 Oct 25.
9
Does Exposure and Response Prevention Behaviorally Activate Patients With Obsessive-Compulsive Disorder? A Preliminary Test.暴露和反应预防行为是否会使强迫症患者激活?初步测试。
Behav Ther. 2019 Jan;50(1):214-224. doi: 10.1016/j.beth.2018.05.007. Epub 2018 Jun 1.
10
Difficult-to-treat pediatric obsessive-compulsive disorder: feasibility and preliminary results of a randomized pilot trial of D-cycloserine-augmented behavior therapy.难治性儿科强迫症:D-环丝氨酸增强行为疗法随机先导试验的可行性和初步结果。
Depress Anxiety. 2013 Aug;30(8):723-31. doi: 10.1002/da.22132. Epub 2013 May 30.

引用本文的文献

1
Hoarding in Children and Adolescents: A Review.儿童和青少年的囤积行为:综述
Child Psychiatry Hum Dev. 2016 Oct;47(5):740-50. doi: 10.1007/s10578-015-0607-2.
2
Residential treatment outcomes for adolescents with obsessive-compulsive disorder.强迫症青少年的住院治疗结果。
Psychother Res. 2016 Nov;26(6):727-36. doi: 10.1080/10503307.2015.1065022. Epub 2015 Aug 26.
3
Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive-compulsive disorder.荟萃分析:囤积症状与强迫症治疗效果不佳相关
Mol Psychiatry. 2014 Sep;19(9):1025-30. doi: 10.1038/mp.2014.50. Epub 2014 Jun 10.
4
Evidence base update for psychosocial treatments for pediatric obsessive-compulsive disorder.儿童强迫症心理社会治疗的循证更新
J Clin Child Adolesc Psychol. 2014;43(1):7-26. doi: 10.1080/15374416.2013.804386. Epub 2013 Jun 9.
5
A review of obsessive-compulsive disorder in children and adolescents.儿童及青少年强迫症综述
Dialogues Clin Neurosci. 2011;13(4):401-11. doi: 10.31887/DCNS.2011.13.4/bboileau.

本文引用的文献

1
Treatment-resistant Obsessive-compulsive Disorder in Young People: Assessment and Treatment Strategies.青少年难治性强迫症:评估与治疗策略
Child Adolesc Ment Health. 2010 Feb;15(1):2-11. doi: 10.1111/j.1475-3588.2009.00548.x. Epub 2009 Oct 27.
2
Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder.强迫障碍患者接受 SRI 药物治疗反应的维度预测因子。
J Affect Disord. 2010 Feb;121(1-2):175-9. doi: 10.1016/j.jad.2009.06.010. Epub 2009 Jul 3.
3
Pharmacotherapy in paediatric obsessive-compulsive disorder: a naturalistic, retrospective study.儿童强迫症的药物治疗:一项自然主义的回顾性研究。
CNS Drugs. 2009;23(3):241-52. doi: 10.2165/00023210-200923030-00005.
4
Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.认知行为疗法、舍曲林或两者联合用于儿童焦虑症治疗
N Engl J Med. 2008 Dec 25;359(26):2753-66. doi: 10.1056/NEJMoa0804633. Epub 2008 Oct 30.
5
Predictors of treatment response in pediatric obsessive-compulsive disorder.儿童强迫症治疗反应的预测因素
J Am Acad Child Adolesc Psychiatry. 2008 Aug;47(8):868-78. doi: 10.1097/CHI.0b013e3181799ebd.
6
Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder.小儿强迫症随机对照治疗试验的荟萃分析。
J Child Psychol Psychiatry. 2008 May;49(5):489-98. doi: 10.1111/j.1469-7610.2007.01875.x.
7
Do all obsessive-compulsive disorder subtypes respond to medication?所有强迫症亚型都对药物治疗有反应吗?
Int Rev Psychiatry. 2008 Apr;20(2):189-93. doi: 10.1080/09540260801889153.
8
Impact of comorbidity on cognitive-behavioral therapy response in pediatric obsessive-compulsive disorder.共病对儿童强迫症认知行为疗法反应的影响。
J Am Acad Child Adolesc Psychiatry. 2008 May;47(5):583-592. doi: 10.1097/CHI.0b013e31816774b1.
9
Family-based cognitive-behavioral therapy for pediatric obsessive-compulsive disorder: comparison of intensive and weekly approaches.针对儿童强迫症的基于家庭的认知行为疗法:强化治疗与每周治疗方法的比较。
J Am Acad Child Adolesc Psychiatry. 2007 Apr;46(4):469-478. doi: 10.1097/chi.0b013e31803062e7.
10
Evaluation of exposure with response-prevention for obsessive compulsive disorder in childhood and adolescence.儿童和青少年强迫症暴露与反应阻止疗法的评估
J Behav Ther Exp Psychiatry. 2008 Mar;39(1):11-22. doi: 10.1016/j.jbtep.2006.11.002. Epub 2007 Jan 4.

暴露和反应预防在自然群体格式中成功实施治疗儿科 OCD 的证据。

Evidence for successful implementation of exposure and response prevention in a naturalistic group format for pediatric OCD.

机构信息

Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O’Hara St., Pittsburgh, PA 15213, USA.

出版信息

Depress Anxiety. 2011 Apr;28(4):342-8. doi: 10.1002/da.20789. Epub 2011 Feb 24.

DOI:10.1002/da.20789
PMID:21456041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3207204/
Abstract

BACKGROUND

Although exposure and response prevention (ERP) is an effective treatment for youth with obsessive-compulsive disorder (OCD), the majority of studies, randomized clinical trials of individual therapy, find variability in treatment response. We evaluated the potential role of individual differences in OCD presentation, comorbid disorders, age, and gender on treatment effects. Moreover, we examined these potential effects in a group format in a naturalistic, clinic-based sample of patients.

METHODS

Pediatric patients with a DSM-IV diagnosis of OCD (n=41) were treated with ERP in an intensive outpatient community-based program. OCD, mood, and anxiety symptom severity was measured at baseline, during treatment, and at discharge. Trajectories and predictors of treatment outcome were measured using linear growth models.

RESULTS

We found that group-based ERP was effective in reducing pediatric OCD symptom severity in a naturalistic treatment setting irrespective of age or gender. Furthermore, ERP was found to be effective at reducing depressive symptoms but not other anxiety symptoms. We also found inter-individual variability in the discharge levels of contamination, symmetry, and intrusive sexual thoughts and in the rate of severity reduction of intrusive sexual thoughts.

CONCLUSION

Group-based ERP is an effective treatment for children and adolescents with OCD. Several factors, including symptom dimensions and comorbid psychopathology, are associated with treatment response and outcome in this pediatric population.

摘要

背景

尽管暴露和反应预防(ERP)是治疗青少年强迫症(OCD)的有效方法,但大多数研究,即个体治疗的随机临床试验,发现治疗反应存在差异。我们评估了 OCD 表现、共病障碍、年龄和性别等个体差异对治疗效果的潜在作用。此外,我们在一个自然主义的、基于诊所的患者群体中以小组形式检查了这些潜在的影响。

方法

在一个以社区为基础的强化门诊计划中,患有 DSM-IV 强迫症诊断的儿科患者接受 ERP 治疗。在基线、治疗期间和出院时测量 OCD、情绪和焦虑症状的严重程度。使用线性增长模型测量治疗结果的轨迹和预测因素。

结果

我们发现,无论年龄或性别如何,基于小组的 ERP 在自然治疗环境中都能有效降低儿科 OCD 症状的严重程度。此外,ERP 被发现可有效降低抑郁症状,但不能降低其他焦虑症状。我们还发现,在出院时的污染、对称和侵入性性思维的严重程度以及侵入性性思维严重程度的降低率方面存在个体间的差异。

结论

基于小组的 ERP 是治疗儿童和青少年 OCD 的有效方法。在这个儿科人群中,包括症状维度和共病精神病理学在内的几个因素与治疗反应和结果有关。