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认知疗法联合暴露反应预防治疗强迫症是否能增强临床疗效?一项社区环境下的随机对照试验。

Does the addition of cognitive therapy to exposure and response prevention for obsessive compulsive disorder enhance clinical efficacy? A randomized controlled trial in a community setting.

机构信息

Frederick W. Thompson Anxiety Disorders Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Department of Psychiatry, University of Toronto, Ontario, Canada.

出版信息

Br J Clin Psychol. 2019 Mar;58(1):1-18. doi: 10.1111/bjc.12188. Epub 2018 Jul 8.

DOI:10.1111/bjc.12188
PMID:29984550
Abstract

OBJECTIVES

Exposure and response prevention (ERP) remains the most empirically supported psychological treatment for obsessive compulsive disorder (OCD). Clinical guidelines recommend the addition of cognitive approaches to ERP although the presumed additive benefits have not been directly tested. The aim of this was to compare a treatment that integrated cognitive therapy with ERP (ERP + CT) to traditional, manualized ERP to test the additive benefits.

DESIGN

A longitudinal, randomized control trial design was used.

METHODS

Participants (N = 127) with OCD were randomly assigned to receive individual outpatient ERP or ERP + CT. Obsessive-compulsive symptom severity measures were completed pre- and post-treatment and at 6-month follow-up.

RESULTS

While both conditions led to significant symptom and obsessive belief reduction, ERP + CT led to significantly greater symptom and belief reduction as compared to ERP across all main symptom presentations of OCD. Based on a priori definitions of effectiveness, more patients in ERP + CT compared to the ERP group were also deemed treatment responders.

CONCLUSIONS

The results of this study suggest that cognitive therapy can be readily integrated with ERP to improve clinical outcomes beyond ERP alone.

PRACTITIONER POINTS

Both ERP and ERP + CT were effective, however a course of ERP + CT was significantly more effective at reducing symptoms of OCD than the ERP treatment condition. Significantly more participants who received ERP + CT experienced clinically significant change in OCD symptoms compared to those who received ERP. OCD symptom dimension did not significantly impact response to either ERP or ERP + CT treatments.

摘要

目的

暴露和反应预防(ERP)仍然是强迫症(OCD)最具经验支持的心理治疗方法。临床指南建议将认知方法添加到 ERP 中,尽管假定的附加益处尚未得到直接测试。本研究旨在比较将认知疗法与 ERP 相结合的治疗方法(ERP+CT)与传统的、规范化的 ERP,以测试附加益处。

设计

采用纵向随机对照试验设计。

方法

将 OCD 患者(N=127)随机分配接受个体门诊 ERP 或 ERP+CT。在治疗前、治疗后和 6 个月随访时完成强迫症症状严重程度测量。

结果

虽然两种治疗方法都导致了显著的症状和强迫观念减轻,但 ERP+CT 导致了比 ERP 更显著的症状和观念减轻,在 OCD 的所有主要症状表现中均如此。根据有效性的预先定义,与 ERP 组相比,ERP+CT 组中有更多的患者被认为是治疗反应者。

结论

这项研究的结果表明,认知疗法可以与 ERP 很容易地整合,以提高临床效果,超出 ERP 单独治疗的效果。

从业者要点

ERP 和 ERP+CT 都有效,但是 ERP+CT 课程在减少 OCD 症状方面比 ERP 治疗条件更为有效。与接受 ERP 治疗的患者相比,接受 ERP+CT 的患者中,有更多的患者在 OCD 症状方面经历了临床显著的变化。OCD 症状维度对 ERP 或 ERP+CT 治疗的反应没有显著影响。

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