Department of Emergency Medicine, Medical University of Vienna, Währinger Gürtel 18-20/6D, 1090 Wien, Austria.
Resuscitation. 2011 Jul;82(7):869-73. doi: 10.1016/j.resuscitation.2011.02.027. Epub 2011 Mar 31.
Body mass index (BMI) may influence the quality of cardiopulmonary resuscitation and may influence prognosis after cardiac arrest. To review the direct effect of obesity on outcome after cardiac arrest, the following cohort study was conducted.
This study based on a cardiac arrest registry comprising all adult patients with cardiac arrest of non-traumatic origin and restoration of spontaneous circulation (ROSC) admitted to the department of emergency medicine of a tertiary-care facility. Data were collected between January 1992 and December 2007 according to the Utstein criteria. We assessed the association between BMI according to the WHO classification (underweight, BMI<18.5; normal weight, 18.5-24.9; overweight, 25.0-29.9; obese ≥ 30), six-month survival and neurological recovery.
Analysis was carried out on a total of 1915 adult patients (32% female). Patients had a median age of 59 years (interquartile range [IQR] 49-70) and a median BMI of 26.0 (IQR 23.9-29.1). Survival to six months was 50%. There was no significant difference in survival between the BMI groups (underweight 46%, normal weight 47%, overweight 52%, obese 51%). In a multivariate analysis neurological outcome was better in overweight patients as compared to subjects with normal BMI (odds ratio 1.35; 95% confidence interval 1.02-1.79).
Body mass index may have no direct influence on six-month survival after cardiac arrest, but patients with moderately elevated BMI may have a better neurological prognosis.
体重指数（BMI）可能会影响心肺复苏的质量，并影响心脏骤停后的预后。为了研究肥胖对心脏骤停后结局的直接影响，进行了这项队列研究。
这项研究基于一个心脏骤停登记处，包含了所有因非创伤性原因导致的心脏骤停且自主循环恢复（ROSC）的成年患者，这些患者被收入三级医疗设施的急诊部门。根据乌斯滕（Utstein）标准，数据收集时间为 1992 年 1 月至 2007 年 12 月。我们评估了根据世界卫生组织（WHO）分类的 BMI（体重不足，BMI<18.5；正常体重，18.5-24.9；超重，25.0-29.9；肥胖≥30）与 6 个月生存率和神经恢复之间的关系。
总共对 1915 名成年患者（32%为女性）进行了分析。患者的中位年龄为 59 岁（四分位距 [IQR] 49-70），BMI 中位数为 26.0（IQR 23.9-29.1）。6 个月生存率为 50%。各 BMI 组之间的生存率无显著差异（体重不足组为 46%，正常体重组为 47%，超重组为 52%，肥胖组为 51%）。在多变量分析中，与 BMI 正常的患者相比，超重患者的神经结局更好（优势比 1.35；95%置信区间 1.02-1.79）。
体重指数可能对心脏骤停后 6 个月的生存率没有直接影响，但 BMI 适度升高的患者可能具有更好的神经预后。
