Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, INF 110, 69120 Heidelberg, Germany.
Eur J Radiol. 2012 Jun;81(6):1165-72. doi: 10.1016/j.ejrad.2011.03.022. Epub 2011 Mar 31.
To describe angiographic, macroscopic and microscopic features of super-micro-bland particle embolization in combination with RF-ablation in kidneys. Thereby, a special focus was given on the impact of the sequence of the different procedural steps.
In ten pigs, super-micro-bland particle embolization combined with RF-ablation was carried out. Super-micro-bland embolization was performed with spherical particles of very small size and tight calibration (40 ± 10 μm). In the left kidneys, RF-ablations were performed before embolization (I). In the right kidneys, RF-ablations were performed after embolization (II). The animals were killed three hours after the procedures. Angiographic (e.g. vessel architecture), macroscopic (e.g. long and short axes of the RF-ablations) and microscopic (e.g. particle distribution) study goals were defined.
Angiography detected almost no vessels in the center of the RF-ablations in I. In II, angiography could not define the RF-ablations. Macroscopy detected significantly larger long and short axes of the RF-ablations in II compared to I (52.2 ± 3.2 mm vs. 45.3 ± 6.9 mm [P<0.05] and 25.1 ± 3.5mm vs. 20.0 ± 1.9 mm [P<0.01], respectively). Microscopy detected irregular particle distribution at the rim of the RF-ablations in I. In II, microscopy detected homogeneous particle distribution at the rim of the RF-ablations. Microscopy detected no particles in the center of the RF-ablations in I and II.
The sequence of the different procedural steps of super-micro-bland particle embolization combined with RF-ablation impacts angiographic, macroscopic and microscopic features in kidneys in the acute setting.
描述超微平滑粒子栓塞联合射频消融治疗肾脏的血管造影、大体和微观特征。因此，特别关注不同操作步骤顺序的影响。
在 10 头猪中进行超微平滑粒子栓塞联合射频消融术。超微平滑栓塞采用非常小尺寸和紧密校准的球形粒子（40 ± 10 μm）进行。在左肾中，在栓塞前进行射频消融（I）。在右肾中，在栓塞后进行射频消融（II）。术后 3 小时处死动物。定义了血管造影（如血管结构）、大体（如射频消融的长轴和短轴）和微观（如粒子分布）研究目标。
血管造影在 I 中几乎未检测到射频消融中心的血管。在 II 中，血管造影无法确定射频消融的位置。大体检查在 II 中比 I 中检测到明显更大的射频消融长轴和短轴（52.2 ± 3.2 mm 比 45.3 ± 6.9 mm [P<0.05] 和 25.1 ± 3.5mm 比 20.0 ± 1.9 mm [P<0.01]）。在 I 中，在射频消融的边缘检测到不规则的粒子分布。在 II 中，在射频消融的边缘检测到均匀的粒子分布。在 I 和 II 中，在射频消融的中心未检测到粒子。
超微平滑粒子栓塞联合射频消融术不同操作步骤的顺序会影响肾脏的急性血管造影、大体和微观特征。
