Instituto de Biología Molecular y Celular de Plantas, CSIC-UPV, Ingeniero Fausto Elio s/n, 46022 València, Spain.
Curr Opin Plant Biol. 2011 Aug;14(4):372-7. doi: 10.1016/j.pbi.2011.03.013. Epub 2011 Mar 30.
Omic approaches to the analysis of plant-virus interactions are becoming increasingly popular. These types of data, in combination with models of interaction networks, will aid in revealing not only host components that are important for the virus life cycle, but also general patterns about the way in which different viruses manipulate host regulation of gene expression for their own benefit and possible mechanisms by which viruses evade host defenses. Here, we review studies identifying host genes regulated by viruses and discuss how these genes integrate in host regulatory and interaction networks, with a particular focus on the physical properties of these networks.
植物-病毒相互作用的分析方法正变得越来越流行。这些类型的数据，结合相互作用网络的模型，将有助于揭示不仅对病毒生命周期很重要的宿主成分，还揭示了不同病毒为自身利益操纵宿主基因表达调控的一般模式，以及病毒逃避宿主防御的可能机制。在这里，我们回顾了鉴定受病毒调控的宿主基因的研究，并讨论了这些基因如何整合到宿主调控和相互作用网络中，特别关注这些网络的物理性质。
