MicroRNA 历史：发现、最新应用和未来前沿。
MicroRNA history: discovery, recent applications, and next frontiers.
机构信息
Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
出版信息
Mutat Res. 2011 Dec 1;717(1-2):1-8. doi: 10.1016/j.mrfmmm.2011.03.009. Epub 2011 Mar 30.
PMID:21458467
Abstract
Since 1993, when the first small non-coding RNA was identified, our knowledge about microRNAs has grown exponentially. In this review, we focus on the main progress in this field and discuss the most important findings under a historical perspective. In addition, we examine microRNAs as markers of disease diagnosis and prognosis, and as new therapeutic targets.
摘要
自 1993 年首次鉴定出第一个小非编码 RNA 以来，我们对 microRNAs 的认识已经呈指数级增长。在这篇综述中，我们专注于该领域的主要进展，并从历史角度讨论最重要的发现。此外，我们还研究了 microRNAs 作为疾病诊断和预后的标志物，以及作为新的治疗靶点。
Zotero 插件