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黏膜相关恒定 T 细胞与感染的免疫应答。

Mucosal associated invariant T cells and the immune response to infection.

机构信息

Pulmonary & Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail code VA R&D 11, Portland, OR 97239, USA.

出版信息

Microbes Infect. 2011 Aug;13(8-9):742-8. doi: 10.1016/j.micinf.2011.03.007. Epub 2011 Mar 31.

DOI:10.1016/j.micinf.2011.03.007
PMID:21458588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3130845/
Abstract

Mucosal associated invariant T cells are unique T cells localized at high frequencies at the portals of entry for many pathogens. Mucosal associated invariant T cells display a variety of characteristics that suggest their function is to act as effectors in the initial control of microbial infection at mucosal sites.

摘要

黏膜相关恒定 T 细胞是一类独特的 T 细胞，它们在许多病原体进入人体的门户处高频分布。黏膜相关恒定 T 细胞表现出多种特征，提示其功能是作为黏膜部位微生物感染初始控制的效应细胞发挥作用。

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本文引用的文献

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Mol Immunol. 2011 Feb;48(5):769-75. doi: 10.1016/j.molimm.2010.12.002. Epub 2010 Dec 28.
2
Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.人类 MAIT 细胞是对异源物有抗性的、组织靶向的、CD161hi 白细胞介素-17 分泌的 T 细胞。
Blood. 2011 Jan 27;117(4):1250-9. doi: 10.1182/blood-2010-08-303339. Epub 2010 Nov 17.
3
Host-bacterial symbiosis in health and disease.宿主-细菌共生在健康和疾病中的作用。
Adv Immunol. 2010;107:243-74. doi: 10.1016/B978-0-12-381300-8.00008-3.
4
Human mucosal associated invariant T cells detect bacterially infected cells.人黏膜相关恒定 T 细胞可检测细菌感染的细胞。
PLoS Biol. 2010 Jun 29;8(6):e1000407. doi: 10.1371/journal.pbio.1000407.
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Vet Res. 2010 Sep-Oct;41(5):62. doi: 10.1051/vetres/2010034. Epub 2010 May 31.
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