Hôpitaux Universitaires de Strasbourg, Clinique Psychiatrique, Hôpital Civil, 1 Place de l'Hôpital, Université de Strasbourg, Faculté de Médecine, INSERM U666, Strasbourg Cedex, France.
Conscious Cogn. 2011 Sep;20(3):703-11. doi: 10.1016/j.concog.2010.12.004. Epub 2011 Apr 2.
Schizophrenia is a severe mental illness affecting sense of identity. Autobiographical memory deficits observed in schizophrenia could contribute to this altered sense of identity. The ability to give a meaning to personally significant events (meaning making) is also critical for identity construction and self-coherence. Twenty-four patients with schizophrenia and 24 control participants were asked to recall five self-defining memories. We assessed meaning making in participants' narratives (spontaneous meaning making) and afterwards asked them explicitly to give a meaning to their memories (cued meaning making). We found that both spontaneous and cued meaning making were impaired in patients with schizophrenia. This impairment was correlated with executive dysfunctions and level of negative symptoms. Our results suggest that patients' difficulties in drawing lessons about past experiences could contribute to explain the lack of coherence observed in their life trajectories and their impaired social adjustment abilities. Implications for psychotherapy are also discussed.
精神分裂症是一种严重的精神疾病，会影响身份认同感。精神分裂症患者中观察到的自传体记忆缺陷可能导致这种身份认同感的改变。赋予个人重要事件意义的能力（意义建构）对于身份构建和自我一致性也至关重要。我们要求 24 名精神分裂症患者和 24 名对照组参与者回忆五个自我定义的记忆。我们评估了参与者叙述中的意义建构（自发意义建构），然后要求他们明确为自己的记忆赋予意义（提示意义建构）。我们发现精神分裂症患者的自发和提示意义建构都受损。这种损伤与执行功能障碍和负性症状水平有关。我们的结果表明，患者从过去经验中吸取教训的困难可能导致他们的生活轨迹缺乏一致性，以及他们社会适应能力受损。还讨论了心理治疗的意义。
