Department of Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, The Netherlands.
Eur J Pain. 2011 Oct;15(9):971-5. doi: 10.1016/j.ejpain.2011.02.008. Epub 2011 Apr 2.
The objective of this study was to investigate the association between psychological factors and complex regional pain syndrome type 1 (CRPS1). A prospective multicenter cohort study was performed involving the emergency room of three hospitals, and patients age 18years or older, with a single fracture, were included in the study. At baseline (T0), participants completed a questionnaire covering demographic, psychological (Symptom Checklist-90), and medical variables. At plaster removal (T1) and at T2, the participants completed a questionnaire addressing symptoms of CRPS1. Psychological factors that were analysed were agoraphobia, depression, somatization, insufficiency, (interpersonal) sensitivity, insomnia, and life events. In total, 596 consecutive patients were included in the study, and 7.0% were diagnosed with CRPS1. None of the psychological factors predicted the development of CRPS1. The scores on the Symptom Checklist-90 subscales fell into the range of the general population and were, in most cases, average or below average when compared with those of pain patients or psychiatric patients. No empirical evidence supports a diagnosis of CRPS1 patients as psychologically different, and the current results indicate that there is no association between psychological factors and CRPS1.
本研究旨在探讨心理因素与 1 型复杂性区域疼痛综合征（CRPS1）之间的关联。采用前瞻性多中心队列研究方法，纳入了三家医院急诊科的年龄在 18 岁及以上、单一骨折的患者。在基线（T0）时，参与者完成了一份涵盖人口统计学、心理学（症状清单-90）和医学变量的问卷。在拆除石膏时（T1）和 T2，参与者完成了一份评估 CRPS1 症状的问卷。分析的心理因素包括广场恐怖症、抑郁、躯体化、不足、（人际）敏感、失眠和生活事件。共有 596 例连续患者纳入研究，其中 7.0%被诊断为 CRPS1。没有任何心理因素预测 CRPS1 的发展。症状清单-90 子量表的得分处于一般人群范围内，与疼痛患者或精神科患者相比，大多数情况下处于平均或低于平均水平。没有实证证据支持将 CRPS1 患者诊断为心理上的差异，目前的结果表明，心理因素与 CRPS1 之间没有关联。
