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J Clin Endocrinol Metab. 2010 Jan;95(1):143-50. doi: 10.1210/jc.2009-0435. Epub 2009 Nov 19.
2
Obesity and excessive daytime sleepiness in prepubertal children with obstructive sleep apnea.阻塞性睡眠呼吸暂停的青春期前儿童的肥胖与日间过度嗜睡
Pediatrics. 2009 Jan;123(1):13-8. doi: 10.1542/peds.2008-0228.
3
Blood pressure associated with sleep-disordered breathing in a population sample of children.儿童群体样本中与睡眠呼吸紊乱相关的血压
Hypertension. 2008 Nov;52(5):841-6. doi: 10.1161/HYPERTENSIONAHA.108.116756. Epub 2008 Oct 6.
4
ADHD subtypes and comorbid anxiety, depression, and oppositional-defiant disorder: differences in sleep problems.注意力缺陷多动障碍亚型与共病的焦虑、抑郁和对立违抗障碍:睡眠问题的差异
J Pediatr Psychol. 2009 Apr;34(3):328-37. doi: 10.1093/jpepsy/jsn083. Epub 2008 Aug 1.
5
Nonsignificance of sleep relative to IQ and neuropsychological scores in predicting academic achievement.睡眠在预测学业成绩方面相对于智商和神经心理学分数的无显著意义。
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Lack of regular exercise, depression, and degree of apnea are predictors of excessive daytime sleepiness in patients with sleep apnea: sex differences.缺乏规律运动、抑郁以及呼吸暂停程度是睡眠呼吸暂停患者日间过度嗜睡的预测因素:性别差异。
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Sleep and behavioral/emotional problems in children: a population-based study.儿童睡眠与行为/情绪问题:一项基于人群的研究。
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Subjective sleepiness and polysomnographic correlates in children scheduled for adenotonsillectomy vs other surgical care.计划接受腺样体扁桃体切除术的儿童与接受其他外科治疗的儿童的主观嗜睡情况及多导睡眠图相关性
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在社区儿童样本中,日间过度嗜睡的患病率及其危险因素:肥胖、哮喘、焦虑/抑郁和睡眠的作用。

Prevalence and risk factors of excessive daytime sleepiness in a community sample of young children: the role of obesity, asthma, anxiety/depression, and sleep.

机构信息

Sleep Research and Treatment Center, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

出版信息

Sleep. 2011 Apr 1;34(4):503-7. doi: 10.1093/sleep/34.4.503.

DOI:10.1093/sleep/34.4.503
PMID:21461329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3065261/
Abstract

STUDY OBJECTIVES

We investigated the prevalence and association of excessive daytime sleepiness (EDS) with a wide range of factors (e.g., medical complaints, obesity, objective sleep [including sleep disordered breathing], and parent-reported anxiety/depression and sleep difficulties) in a large general population sample of children. Few studies have researched the prevalence and predictors of EDS in young children, none in a general population sample of children, and the results are inconsistent.

DESIGN

Cross-sectional

SETTING

Population -based.

PARTICIPANTS

508 school-aged children from the general population.

INTERVENTIONS

N/A.

MEASUREMENTS AND RESULTS

Children underwent a 9-hour polysomnogram (PSG), physical exam, and parent completed health, sleep and psychological questionnaires. Children were divided into 2 groups: those with and without parent reported EDS. The prevalence of subjective EDS was approximately 15%. Significant univariate relationships were found between children with EDS and BMI percentile, waist circumference, heartburn, asthma, and parent reported anxiety/depression, and sleep difficulties. The strongest predictors of EDS were waist circumference, asthma, and parent-reported symptoms of anxiety/depression and trouble falling asleep. All PSG sleep variables including apnea/hypopnea index, caffeine consumption, and allergies were not significantly related to EDS.

CONCLUSIONS

It appears that the presence of EDS is more strongly associated with obesity, asthma, parent reported anxiety/depression, and trouble falling asleep than with sleep disordered breathing (SDB) or objective sleep disruption per se. Our findings suggest that children with EDS should be thoroughly assessed for anxiety/depression, nocturnal sleep difficulties, asthma, obesity, and other metabolic factors, whereas objective sleep findings may not be as clinically useful.

摘要

研究目的

我们调查了大样本儿童人群中,日间嗜睡(EDS)与广泛因素(如医疗投诉、肥胖、客观睡眠[包括睡眠呼吸障碍]以及父母报告的焦虑/抑郁和睡眠困难)的患病率和相关性。很少有研究调查幼儿 EDS 的患病率和预测因素,也没有研究在一般儿童人群样本中进行,结果也不一致。

设计

横断面研究

设置

基于人群。

参与者

来自普通人群的 508 名学龄儿童。

干预措施

无。

测量和结果

儿童接受了 9 小时多导睡眠图(PSG)、体检和父母完成的健康、睡眠和心理问卷。儿童分为两组:有和没有父母报告的 EDS。主观 EDS 的患病率约为 15%。在有无 EDS 的儿童中,存在显著的单变量关系,包括 BMI 百分位数、腰围、烧心、哮喘和父母报告的焦虑/抑郁以及睡眠困难。EDS 的最强预测因素是腰围、哮喘以及父母报告的焦虑/抑郁和入睡困难的症状。所有 PSG 睡眠变量,包括呼吸暂停/低通气指数、咖啡因摄入量和过敏,与 EDS 无显著相关性。

结论

似乎 EDS 的存在与肥胖、哮喘、父母报告的焦虑/抑郁和入睡困难的关系比与睡眠呼吸障碍(SDB)或客观睡眠障碍本身更密切。我们的研究结果表明,有 EDS 的儿童应全面评估焦虑/抑郁、夜间睡眠困难、哮喘、肥胖和其他代谢因素,而客观睡眠发现可能没有临床价值。