Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Rheumatol Int. 2012 Jul;32(7):1955-62. doi: 10.1007/s00296-011-1894-y. Epub 2011 Apr 3.
The aim of the study was to determine the economical impact of juvenile idiopathic arthritis (JIA) and familial Mediterranean fever (FMF) in Turkey. A total of 100 patients (69 F/31 M) with JIA and 100 with FMF (68 F/32 F) who were consecutively seen in the outpatient clinic of the pediatric rheumatology department at Cerrahpasa Medical School between August 2008 and January 2009 were studied. Cost data were collected through a questionnaire filled out by the parents. The mean age (JIA: 11 ± 5 years; FMF:12 ± 4 years) and mean disease duration (JIA:5 ± 3 years; FMF: 4 ± 3 years) of the patients were similar. JIA patients were assigned to 5 subtypes (polyarticular: n = 45, oligoarticular: n = 30, systemic onset: n = 13, psoriatic: n = 6, and enthesopathy-related JIA: n = 6). Forty-nine percent of the patients with JIA were treated with anti-TNF drugs and 61% with DMARDs. All patients with FMF were using colchicine. The total annual cost of JIA (
本研究旨在评估幼年特发性关节炎(JIA)和家族性地中海热(FMF)在土耳其的经济影响。2008 年 8 月至 2009 年 1 月期间,我们连续在切拉庞萨医学院儿科风湿病科的门诊对 100 名 JIA 患者(69 名女性/31 名男性)和 100 名 FMF 患者(68 名女性/32 名男性)进行了研究。通过家长填写的问卷收集成本数据。患者的平均年龄(JIA:11 ± 5 岁;FMF:12 ± 4 岁)和平均病程(JIA:5 ± 3 年;FMF:4 ± 3 年)相似。JIA 患者分为 5 个亚型(多关节炎:n = 45,少关节炎:n = 30,全身型:n = 13,银屑病关节炎:n = 6,附着点相关关节炎:n = 6)。49%的 JIA 患者接受 TNF 拮抗剂治疗,61%接受 DMARD 治疗。所有 FMF 患者均使用秋水仙碱。JIA 的年总费用(