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关于单侧隐睾症男孩是否需要激素治疗的争议仍在继续:文献综述。

The controversy regarding the need for hormonal treatment in boys with unilateral cryptorchidism goes on: a review of the literature.

机构信息

Kinderchirurgie und Kinderurologie, Kinderkrankenhaus auf der Bult, Janusz-Korszak-Allee 12, Hannover, Germany.

出版信息

Eur J Pediatr. 2013 Jan;172(1):5-8. doi: 10.1007/s00431-012-1711-y. Epub 2012 Mar 7.

DOI:10.1007/s00431-012-1711-y
PMID:22395567
Abstract

Hormonal treatment for unilateral undescended testes continues to be recommended in some countries. We reviewed the literature in favor and against this recommendation. Since the paternity rate of men with a history of unilateral undescended testes only treated with surgery is normal, the effectiveness of hormonal treatment to produce testicular descent is low, the cost is considerable, and there are potential adverse effects, hormonal treatment for boys with unilateral undescended testes should no longer be recommended.

摘要

在一些国家,仍然推荐对单侧隐睾进行激素治疗。我们回顾了支持和反对这一建议的文献。由于仅接受手术治疗的单侧隐睾男性的生育力正常,因此激素治疗使睾丸下降的效果较低,成本相当高,且存在潜在的不良反应,因此不应再推荐对单侧隐睾男孩进行激素治疗。

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本文引用的文献

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Management of cryptorchidism: a survey of clinical practice in Italy.隐睾症的管理:意大利临床实践调查。
BMC Pediatr. 2012 Jan 10;12:4. doi: 10.1186/1471-2431-12-4.
2
A critical appraisal of the evidence for improved fertility indices in undescended testes after gonadotrophin-releasing hormone therapy and orchidopexy.促性腺激素释放激素治疗和睾丸固定术治疗未降睾丸后生育指数改善的证据的批判性评价。
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World Health Organization reference values for human semen characteristics.
一项评估促黄体生成素释放激素疗法对隐睾症患儿疗效的比较研究的系统评价和荟萃分析。
Int Urol Nephrol. 2016 May;48(5):635-44. doi: 10.1007/s11255-016-1235-x. Epub 2016 Feb 22.
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[Undescended testis: current treatment guidelines].[隐睾:当前治疗指南]
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Operative management of cryptorchidism: guidelines and reality--a 10-year observational analysis of 3587 cases.隐睾症的手术治疗:指南与现实——对3587例病例的10年观察分析
BMC Pediatr. 2015 Sep 10;15:116. doi: 10.1186/s12887-015-0429-1.
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A cross-sectional study of cryptorchidism in children: testicular volume and hormonal function at 18 years of age.一项关于儿童隐睾症的横断面研究:18岁时的睾丸体积和激素功能。
Int Braz J Urol. 2015 Jan-Feb;41(1):57-66. doi: 10.1590/S1677-5538.IBJU.2015.01.09.
7
The timing of surgery for undescended testis - a retrospective multicenter analysis.隐睾手术时机——一项回顾性多中心分析
Dtsch Arztebl Int. 2014 Sep 26;111(39):649-57. doi: 10.3238/arztebl.2014.0649.
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Effects on normalized testicular atrophy index (TAIn) in cryptorchid infants treated with GnRHa pre and post-operative vs surgery alone: a prospective randomized trial and long-term follow-up on 62 cases.GnRHa术前及术后治疗与单纯手术治疗对隐睾婴儿标准化睾丸萎缩指数(TAIn)的影响:一项对62例患者的前瞻性随机试验及长期随访
Pediatr Surg Int. 2014 Oct;30(10):1061-7. doi: 10.1007/s00383-014-3577-8. Epub 2014 Aug 9.
9
Neoadjuvant human Chorionic Gonadotropin (hCG) therapy may improve the position of undescended testis: a preliminary report.新辅助人绒毛膜促性腺激素(hCG)治疗可能改善隐睾位置:初步报告。
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世界卫生组织人类精液特征参考值。
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4
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5
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[Pediatrics].[儿科学]
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Epidemiology and pathogenesis of cryptorchidism.隐睾症的流行病学与发病机制。
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Age at surgery for undescended testis and risk of testicular cancer.隐睾手术时的年龄与睾丸癌风险
N Engl J Med. 2007 May 3;356(18):1835-41. doi: 10.1056/NEJMoa067588.