刚地弓形虫：ROPl 重组抗原在人类急性弓形虫病免疫球蛋白 G 亲和力检测中的应用。
Toxoplasma gondii: usefulness of ROP1 recombinant antigen in an immunoglobulin G avidity assay for diagnosis of acute toxoplasmosis in humans.
机构信息
Gdańsk University of Technology, Chemical Faculty, Department of Microbiology, Gdańsk, Poland.
出版信息
Pol J Microbiol. 2010;59(4):307-10.
PMID:21466050
Abstract
The results present in this study suggest that the Toxoplasma gondii recombinant ROP1 antigen in an IgG avidity test can be useful for detection of acute stage of infection. Specific antibodies of low avidity were detected in most of the sera from individuals with acute toxoplasmosis, while the absence or specific antibodies of high avidity were detected in sera from patients with chronic infection.
摘要
本研究结果表明，在 IgG 亲和力试验中，弓形虫重组ROP1 抗原可用于检测急性感染阶段。大多数急性弓形虫病患者的血清中检测到低亲和力的特异性抗体，而慢性感染患者的血清中则检测到缺乏或高亲和力的特异性抗体。
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