质子磁共振波谱在鉴别脑肿瘤与非肿瘤性脑病变中的价值。

The value of proton MR-spectroscopy in the differentiation of brain tumours from non-neoplastic brain lesions.

作者信息

Aydin H, Sipahioğlu S, Oktay N Aydin, Altin E, Kizilgöz V, Hekimoglu B

机构信息

Dişkapi Yildirim Beyazit Research Hospital, Radiology Department, Ankara, Turkey.

出版信息

JBR-BTR. 2011 Jan-Feb;94(1):1-10.

PMID:21466053

Abstract

PURPOSE

Our aim was to evaluate the efficacy of Proton-MR Spectroscopy for the differentiation of cranial masses from non-neoplastic brain disorders.

MATERIAL AND METHOD

33 patients with intracranial mass lesions, 29 patients with non-neoplastic brain lesions: Ischemic-demyelinating-metabolic-benign cystic mass group; As a whole 62 patients: 30 males and 32 females were included in this study.

RESULTS

In brain tumours, average Cho/NAA ratio 2.84-NAA/Cr ratio was 0.97, Cho/Cr ratio 2.42 and Cho/MI ratio was 3.51. In non-neoplastic group; NAA/Cr ratio was extremely higher than tumour group, the other ratios were far lower than cranial mass lesions. Average Cho/NAA ratio: 0.50 +/- 0.15, Cho/Cr ratio: 1.05 +/- 0.14, Cho/MI ratio: 1.07 +/- 0.73.

CONCLUSION

Higher Cho/NAA and Cho/MI ratios with lower NAA/Cr ratio were most likely to be malignant. Additional lipid and lactate peaks were generally seen in malignant group.

摘要

目的

我们的目的是评估质子磁共振波谱在鉴别颅内肿块与非肿瘤性脑部疾病方面的疗效。

材料与方法

33例颅内肿块病变患者，29例非肿瘤性脑部病变患者：缺血 - 脱髓鞘 - 代谢 - 良性囊性肿块组；本研究共纳入62例患者，其中男性30例，女性32例。

结果

在脑肿瘤中，平均胆碱/ N - 乙酰天门冬氨酸（Cho/NAA）比值为2.84，N - 乙酰天门冬氨酸/肌酸（NAA/Cr）比值为0.97，胆碱/肌酸（Cho/Cr）比值为2.42，胆碱/肌醇（Cho/MI）比值为3.51。在非肿瘤组中，NAA/Cr比值远高于肿瘤组，其他比值远低于颅内肿块病变组。平均Cho/NAA比值：0.50±0.15，Cho/Cr比值：1.05±0.14，Cho/MI比值：1.07±0.73。