Centro de Estudos em Estresse Oxidativo (CEEO), ICBS-UFRGS, Porto Alegre, Brazil.
Curr Pharm Biotechnol. 2012 Jan;13(1):235-44. doi: 10.2174/138920112798868674.
Over the last few years, samples from the marine environment have been screened for a variety of compounds with different biological activities. Among all marine organisms, sponges represent one of the most promising sources of leads in the research of new cancer drugs. However, there are few reports on screening Brazilian marine sponges for biological activities. In the following review, the current status of natural product research relating to Brazilian marine sponges is summarized, particularly for compounds demonstrating potential antitumor activity.
在过去的几年中，人们已经从海洋环境中筛选出了具有各种生物活性的多种化合物。在所有海洋生物中，海绵是寻找新型抗癌药物的最有希望的先导化合物来源之一。然而，关于筛选巴西海洋海绵的生物活性的报道却很少。在下面的综述中，总结了与巴西海洋海绵相关的天然产物研究的现状，特别是具有潜在抗肿瘤活性的化合物。
