对1994年至2014年间来自海洋海绵的强效抗中枢神经系统肿瘤药物的简要综述。

A brief review of potent anti-CNS tumourics from marine sponges: covering the period from 1994 to 2014.

作者信息

Pejin Boris, Glumac Miodrag

机构信息

a Department of Life Sciences , Institute for Multidisciplinary Research - IMSI, University of Belgrade , Belgrade , Serbia.

b School of Food Science and Biotechnology - SFSB, Food Oral Processing Laboratory , Zhejiang Gongshang University , Hangzhou , People's Republic of China.

出版信息

Nat Prod Res. 2018 Feb;32(4):375-384. doi: 10.1080/14786419.2017.1309400. Epub 2017 Apr 7.

DOI:10.1080/14786419.2017.1309400

PMID:28385035

Abstract

This review covers the 1994-2014 literature data published for anti-CNS tumour natural products isolated from marine sponges. The focus was on highly potent antitumourics. It describes only eight promising bioactives (screened on even less number of the respective cell lines) suggesting that brain tumours actually represent quite a hot topic for the natural product research community worldwide.

摘要

本综述涵盖了1994年至2014年发表的从海洋海绵中分离出的抗中枢神经系统肿瘤天然产物的文献数据。重点是高效抗肿瘤药物。它仅描述了八种有前景的生物活性物质（在更少数量的相应细胞系上进行筛选），这表明脑肿瘤实际上是全球天然产物研究界相当热门的话题。