Department of Psychiatry, University of California, San Francisco, CA 94111, USA.
Psychol Sci. 2011 May;22(5):641-9. doi: 10.1177/0956797611403156. Epub 2011 Apr 5.
Social rejection can create powerful changes in people's brains and bodies. In the study reported here, we examined brain-based individual differences associated with buffering against cardiovascular threat responses to social rejection. Using EEG source-localization techniques, we examined differences in intracortical asymmetry. We predicted that individuals with greater left relative to right dorsolateral prefrontal activity would show a more approach-motivated response to social rejection. Eighty-four female participants were randomly assigned to one of three stressful situations: social rejection, social evaluation without rejection, or self-evaluation. Among participants assigned to the social-rejection condition, greater left relative to right prefrontal intracortical activity at baseline was associated with more adaptive cardiovascular profiles and more self-reported approach-oriented emotions. Participants in the other conditions did not show these relationships. Our data are the first to show that social context matters when attempting to link individual differences in cortical asymmetry with approach-related cardiovascular and emotional outcomes.
社会排斥会在人们的大脑和身体中产生强大的变化。在本报告的研究中，我们研究了与缓冲社会排斥对心血管威胁反应相关的基于大脑的个体差异。我们使用脑电图源定位技术，研究了皮质内不对称的差异。我们预测，与右侧背外侧前额叶活动相比，左侧活动更多的个体在面对社会排斥时会表现出更趋近动机的反应。84 名女性参与者被随机分配到三种压力情境之一：社会排斥、没有排斥的社会评价或自我评价。在被分配到社会排斥情境的参与者中，基线时左侧相对于右侧前额叶皮质内活动的增加与更适应的心血管特征和更多的自我报告趋近导向情绪相关。其他情境中的参与者没有表现出这些关系。我们的数据首次表明，当试图将皮质不对称的个体差异与趋近相关的心血管和情绪结果联系起来时，社会环境很重要。
