Department of Pneumonology, Hospital Sezana, Sezana, Slovenia.
Int J Chron Obstruct Pulmon Dis. 2011;6:141-6. doi: 10.2147/COPD.S16605. Epub 2011 Feb 10.
To determine the importance of spirometric testing for early detection of chronic obstructive pulmonary disease (COPD).
Spirometric testing has been performed annually on World COPD Day in Sezana from 2003. Sezana is in a semiurban region of Slovenia, with 12,000 inhabitants. The investigation was performed between January 2003 and December 2008. In total, 770 persons were enrolled (414 females and 356 males). The participants were recruited by mass media appeals. Smokers aged ≥ 40 years with a smoking history of ≥ 10 pack-years were invited to visit the local chest clinic. The participants completed a questionnaire and had spirometry performed. Subjects with a postbronchodilator forced expiratory volume in one second/forced vital capacity <0.70 were defined as having COPD, according to the Global Initiative for Chronic Obstructive Lung Disease guidelines.
We identified that 16.2% of subjects had impaired lung function. Of these, 10.2% had an obstructive pattern of ventilatory impairment and 6% had a restrictive pattern. We identified 79 individuals with COPD. Subjects with COPD were >70 years in 40.5% in cases. The majority of individuals with COPD were men (74.6%), and 90% were smokers. COPD was mild in 52% of subjects, moderate in 34%, and severe in 14%. The majority of subjects had a milder stage of the disease, and 92% of those with COPD (72/79) had not been recognized to have COPD previously.
These results suggest that spirometry testing could detect patients with COPD in the earlier stages of the disease.
为了确定肺功能检测在慢性阻塞性肺疾病（COPD）早期发现中的重要性。
自 2003 年以来，每年在世界 COPD 日于塞扎纳进行肺功能检测。塞扎纳位于斯洛文尼亚的一个半城市地区，拥有 12000 名居民。该调查于 2003 年 1 月至 2008 年 12 月进行。共有 770 人参加（414 名女性和 356 名男性）。通过大众媒体呼吁招募参与者。邀请年龄≥40 岁且吸烟史≥10 包年的吸烟者到当地胸科诊所就诊。参与者完成一份问卷并进行肺功能检测。根据全球慢性阻塞性肺疾病倡议指南，用力呼气量一秒率/用力肺活量<0.70 的受试者被定义为患有 COPD。
我们发现 16.2%的受试者肺功能受损。其中，10.2%存在通气障碍的阻塞性模式，6%存在限制性模式。我们共发现 79 例 COPD 患者。在这些患者中，40.5%的患者年龄>70 岁。大多数 COPD 患者为男性（74.6%），90%为吸烟者。52%的患者为轻度 COPD，34%为中度，14%为重度。大多数患者处于疾病的较轻阶段，92%（72/79）的 COPD 患者以前未被诊断为 COPD。
这些结果表明肺功能检测可以在疾病的早期阶段发现 COPD 患者。
