Department of Community Dentistry, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
Int J Paediatr Dent. 2011 Sep;21(5):333-41. doi: 10.1111/j.1365-263X.2011.01128.x. Epub 2011 Apr 6.
Predicting risk of posteruptive enamel breakdown (PEB) of molar-incisor hypomineralization (MIH) opacity is a difficult but important clinical task. Therefore, there is a need to evaluate these aspects through longitudinal studies.
The aim of this longitudinal study was to analyse the relationship between colours of MIH opacity of children aged 6-12 (baseline) and other clinical and demographic variables involved in the increase in severity of MIH.
A blinded prospective 18-month follow-up was conducted with 147 individuals presenting mild MIH. Tooth-based incidence of increase in severity of MIH (PEB or atypical restorations) was used as dependent measurement. Enamel opacities were recorded according to colour shades of white, yellow and brown, allowing assessment of susceptibility to structural loss over time, according to colour of MIH opacity. Poisson regression models were used to adjust the results for demographic and clinical variables.
Brown and yellow MIH opacities were at higher risk for PEB and atypical restorations than those of white ones, even after adjustment for clinical and demographic variables.
Teeth presenting mild MIH severity associated with yellow and brown enamel opacities were at high risk for increase in severity of MIH than lighter ones. This result could help clinicians determine a risk-based treatment for children with MIH.
预测磨牙-切牙型低矿化（MIH）釉质不透光性的继发病理性釉质丧失（PEB）风险是一项困难但重要的临床任务。因此，需要通过纵向研究来评估这些方面。
本纵向研究旨在分析儿童 6-12 岁（基线）MIH 不透光性颜色与其他临床和人口统计学变量之间的关系，这些变量涉及 MIH 严重程度的增加。
对 147 名患有轻度 MIH 的个体进行了为期 18 个月的盲法前瞻性随访。以 MIH 严重程度增加（PEB 或非典型修复）的牙为基础的发生率作为因变量。根据 MIH 不透光性的颜色记录釉质变色的白色、黄色和棕色阴影，以评估随时间推移结构丧失的易感性。使用泊松回归模型对人口统计学和临床变量进行结果调整。
棕色和黄色 MIH 不透光性比白色不透光性更容易发生 PEB 和非典型修复，即使在调整了临床和人口统计学变量后也是如此。
与浅色釉质相比，与黄色和棕色釉质变色相关的轻度 MIH 严重程度的牙齿发生 MIH 严重程度增加的风险更高。这一结果有助于临床医生为 MIH 儿童确定基于风险的治疗方法。
