Guangdong Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangdong Guangzhou, China.
Mycologia. 2011 Sep-Oct;103(5):946-9. doi: 10.3852/10-319. Epub 2011 Apr 6.
Eight peptide toxins were isolated and purified from basidiocarps of Amanita exitialis with high performance liquid chromatography and were subjected to ultraviolet, nuclear magnetic resonance and mass spectrometry. We identified seven peptide toxins, α-amanitin, β-amanitin, amaninamide, phallacin, phallacidin, phallisacin and desoxoviroidin. The molecular weight (729.5 Da) of the eighth compound did not match that of any reported Amanita toxins and, although the UV absorption spectrum indicated it to be a phallotoxin, further studies are required to identify this component. This is the first report of amaninamide, phallacin, phallisacin and desoxoviroidin in this lethal mushroom species.
从致命鹅膏菌的担子果中分离纯化了 8 种肽类毒素，运用高效液相色谱、紫外光谱、核磁共振和质谱技术对其进行了结构鉴定，分别为α-鹅膏肽、β-鹅膏肽、鹅膏蕈氨酸、蝇蕈醇、蝇蕈氨酸、蝇蕈毒肽和去氧鬼笔环肽。第 8 个化合物的分子量（729.5 Da）与任何已报道的鹅膏菌毒素均不匹配，虽然紫外光谱表明它是一种鹅膏肽，但仍需进一步研究以确定该成分。这是首次在该致死鹅膏菌物种中报道鹅膏蕈氨酸、蝇蕈醇、蝇蕈毒肽和去氧鬼笔环肽。
