First Department of Internal Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Circ J. 2011;75(5):1080-9. doi: 10.1253/circj.cj-10-0742. Epub 2011 Apr 7.
Atrial tachycardia (AT) occurring during atrial fibrillation (AF) ablation is sometimes difficult to identify and eliminate. EnSite Array (EA) visualizes beat-to-beat virtual activation of AT. The aim of the present study was to characterize AT occurring during AF ablation during ongoing AF, using EA.
Among 90 patients with AF (paroxysmal, n=67; persistent, n=23) who underwent radiofrequency catheter ablation during ongoing AF, 33 (37%) had 46 ATs that developed during ablation, and 9 (10%) of these patients had 9 ATs that developed before ablation. AT was sustained in 39 and non-sustained in 7. Nineteen ATs resulted from a focal mechanism and 27 from macroreentry. The major AT foci were distributed in the pulmonary vein (n = 8) and left atrial roof (n = 3), and macroreentrant ATs mainly consisted of peri-mitral AT (n = 10), common atrial flutter (n = 10), and roof reentrant AT (n = 3). After EA-guided ablation of AT, 41 ATs in 28 patients (85%) were eventually rendered non-inducible. During 21 ± 8 months of follow-up, 30 of the 33 patients (91%) were free from AF/AT recurrence.
AT occurred in 37% of the patients during ongoing AF ablation, resulting from a focal or reentrant mechanism in diverse locations. Peri-mitral AT, common atrial flutter, and AT from the pulmonary vein were frequently observed. These ATs were eliminated by EA-guided radiofrequency ablation in most cases.
心房颤动(AF)消融过程中出现的房性心动过速(AT)有时难以识别和消除。EnSite Array(EA)可实时显示 AT 的虚拟激活情况。本研究旨在使用 EA 对 AF 消融过程中持续 AF 时发生的 AT 进行特征描述。
在 90 例正在进行 AF 消融的 AF 患者(阵发性,n=67;持续性,n=23)中,有 33 例(37%)发生 46 次 AT,其中 9 例(10%)患者在消融前发生 9 次 AT。39 次 AT 持续存在,7 次非持续存在。19 次 AT 源于局灶性机制,27 次源于大折返。主要 AT 病灶分布在肺静脉(n=8)和左心房顶部(n=3),大折返性 AT 主要由二尖瓣环周围 AT(n=10)、常见房性心动过速(n=10)和房顶折返性 AT(n=3)组成。在 EA 指导下消融 AT 后,28 例患者(85%)中的 41 次 AT 最终变得不可诱导。在 21±8 个月的随访中,33 例患者中的 30 例(91%)无 AF/AT 复发。
在持续进行的 AF 消融过程中,37%的患者发生 AT,其机制为局灶性或折返性,病灶分布广泛。二尖瓣环周围 AT、常见房性心动过速和肺静脉起源的 AT 较为常见。这些 AT 大多数通过 EA 引导的射频消融得以消除。