Mossman D, Somoza E
Department of Psychiatry, University of Cincinnati Medical Center, OH 45267-0559.
J Affect Disord. 1990 Sep;20(1):13-8. doi: 10.1016/0165-0327(90)90045-a.
Some investigators have reported that dexamethasone suppression test (DST) accuracy might be improved by incorporating dexamethasone concentrations ([dex]) into test results. Using receiver operating characteristic methods, we evaluated data from four studies in which cortisol and dexamethasone levels were measured simultaneously at one or more times after drug ingestion. We compared DST accuracy using cortisol alone with various diagnostic indices incorporating [dex]. In none of the 21 comparisons did the [dex] factor enhance diagnostic performance.
一些研究人员报告称，通过将地塞米松浓度（[dex]）纳入测试结果，地塞米松抑制试验（DST）的准确性可能会提高。我们使用接受者操作特征方法，评估了四项研究的数据，这些研究在服药后一个或多个时间点同时测量了皮质醇和地塞米松水平。我们将仅使用皮质醇的DST准确性与纳入[dex]的各种诊断指标进行了比较。在21项比较中，[dex]因素均未提高诊断性能。
