Conesa Xavier, Seijas Roberto, Ares Oscar, Huguet Pere, Perez-Dominguez Manuel
Hospital Vall d'Hebron, Barcelona, Spain.
Acta Orthop Belg. 2011 Feb;77(1):9-14.
Liposarcoma is one of the most common malignant soft tissue tumours. It usually presents as a single mass, and the prognosis varies according to the degree of histological differentiation. Multicentric liposarcoma is an unusual presentation of this tumour in which several independent lesions develop and generally display an aggressive pattern. It may be difficult to establish a precise diagnosis because of the problems differentiating between recurrence or metastasis of a single liposarcoma and multicentric primary lesions. A systematic review was undertaken, assessing articles on multicentric liposarcoma, with emphasis on the diagnostic criteria and treatment for this condition. Illustrative cases of multicentric liposarcoma from our Institution are presented.
脂肪肉瘤是最常见的恶性软组织肿瘤之一。它通常表现为单个肿块,预后根据组织学分化程度而异。多中心性脂肪肉瘤是这种肿瘤的一种不寻常表现形式,其中会出现几个独立的病灶,并且通常呈现侵袭性模式。由于难以区分单发性脂肪肉瘤的复发或转移与多中心原发性病灶,因此可能难以做出准确诊断。我们进行了一项系统综述,评估有关多中心性脂肪肉瘤的文章,重点关注这种疾病的诊断标准和治疗方法。本文还展示了我们机构多中心性脂肪肉瘤的典型病例。