Salemis Nikolaos S, Seretis Charalambos, Seretis Fotios, Christofyllakis Charalambos, Karalis Georgios
Department of Surgery, Army General Hospital, Athens, Greece, Europe.
Department of Medical Oncology, Army General Hospital, Athens, Greece, Europe.
J Nat Sci Biol Med. 2014 Jan;5(1):186-90. doi: 10.4103/0976-9668.127325.
Multifocal soft tissue sarcoma is a rare clinical entity occurring in 1% of patients with extremity soft tissue sarcoma and in 4.5% of patients with liposarcoma. Multifocal disease may arise either synchronously or metachronously and has been associated with poor prognosis. Herein, we have described a rare case of metachronous multifocal myxoid liposarcoma involving the gastrointestinal tract that developed 14 months after the resection of a myxoid buttock liposarcoma. Diagnostic evaluation and management of the patient are discussed along with a review of the relevant literature. We conclude that multifocal myxoid liposarcoma is a rare clinical entity that usually represents metastatic disease with poor prognosis. A thorough imaging and careful physical examination are essential in the preoperative evaluation and postoperative follow-up of patients with myxoid extremity liposarcomas, as these tumors are known to have a tendency to spread toward extrapulmonary sites, frequently without pulmonary metastases.
多灶性软组织肉瘤是一种罕见的临床实体，在1%的肢体软组织肉瘤患者和4.5%的脂肪肉瘤患者中出现。多灶性疾病可同时或异时发生，且与预后不良相关。在此，我们描述了一例罕见的异时性多灶性黏液样脂肪肉瘤累及胃肠道的病例，该病例在臀部黏液样脂肪肉瘤切除术后14个月发生。本文讨论了该患者的诊断评估和治疗，并对相关文献进行了综述。我们得出结论，多灶性黏液样脂肪肉瘤是一种罕见的临床实体，通常代表预后不良的转移性疾病。对于黏液样肢体脂肪肉瘤患者，全面的影像学检查和仔细的体格检查在术前评估和术后随访中至关重要，因为已知这些肿瘤有向肺外部位扩散的倾向，且常常没有肺转移。
