Pediatrics Unit, S.Chiara Hospital of Trento, Largo Medaglie d'Oro 9, 38122 Trento, Italy.
Ital J Pediatr. 2011 Apr 7;37:15. doi: 10.1186/1824-7288-37-15.
despite recent progress in imaging, it is still difficult to distinguish between pituitary adenoma and hyperplasia, even using Magnetic Resonance Imaging (MRI) with gadolinium injection. We describe an example of reactive pituitary hyperplasia from primary hypothyroidism that mimicked a pituitary macroadenoma in a child.
a 10 year old boy presented with headache and statural growth arrest. MRI revealed an intrasellar and suprasellar pituitary mass. Endocrine evaluation revealed primary hypothyroidism.
the patient was started on levothyroxine with resolution of the mass effect.
primary hypothyroidism should be considered in the differential diagnosis of solid mass lesions of the pituitary gland. Examination of thyroid function in patients with sellar and suprasellar masses revealed by MRI may avoid unnecessary operations which can cause irreversible complications.
尽管成像技术最近取得了进展,但即使使用注射钆的磁共振成像(MRI),仍难以区分垂体腺瘤和增生。我们描述了一例由原发性甲状腺功能减退引起的反应性垂体增生,该增生在儿童中类似于垂体大腺瘤。
一名 10 岁男孩出现头痛和身高生长停滞。MRI 显示鞍内和鞍上垂体肿块。内分泌评估显示原发性甲状腺功能减退。
患者开始服用左甲状腺素,肿块效应得到缓解。
在垂体腺固体肿块病变的鉴别诊断中应考虑原发性甲状腺功能减退症。通过 MRI 显示的鞍内和鞍上肿块患者的甲状腺功能检查可能避免了可引起不可逆转并发症的不必要手术。