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[原发性甲状腺功能减退所致垂体增生]

[Pituitary hyperplasia due to primary hypothyroidism].

作者信息

Ammar M, HadjKacem F, Maalej A, Abid G, Charfi N, Abid M

机构信息

Service d'endocrinologie et diabétologie, hôpital Hedi-Chaker, avenue Majida-Boulila, 3029 Sfax, Tunisie.

Service d'endocrinologie et diabétologie, hôpital Hedi-Chaker, avenue Majida-Boulila, 3029 Sfax, Tunisie.

出版信息

Rev Med Interne. 2017 Dec;38(12):844-846. doi: 10.1016/j.revmed.2017.06.007. Epub 2017 Jul 6.

DOI:10.1016/j.revmed.2017.06.007
PMID:28690090
Abstract

INTRODUCTION

Pituitary hyperplasia due to primary hypothyroidism is rare and underdiagnosed.

CASE REPORT

We report an 18-year-old patient referred for a pituitary mass revealing primary hypothyroidism. Biological parameters confirmed severe primary hypothyroidism and hyperprolactinemia. Outcome was favorable with l-thyroxin supplementation resulting in TSH and prolactin levels normalization and pituitary mass resolution.

CONCLUSION

Pituitary hyperplasia due to primary hypothyroidism, although rare, should be recognized to avoid unnecessary surgery leading to irreversible complications.

摘要

引言

原发性甲状腺功能减退所致垂体增生较为罕见且诊断不足。

病例报告

我们报告一名18岁因垂体肿物就诊的患者,检查发现为原发性甲状腺功能减退。生物学指标证实存在严重的原发性甲状腺功能减退和高催乳素血症。补充左旋甲状腺素后情况良好,促甲状腺激素(TSH)和催乳素水平恢复正常,垂体肿物消退。

结论

原发性甲状腺功能减退所致垂体增生虽罕见,但应予以识别,以避免不必要的手术及不可逆并发症。

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[Pituitary hyperplasia due to primary hypothyroidism].[原发性甲状腺功能减退所致垂体增生]
Rev Med Interne. 2017 Dec;38(12):844-846. doi: 10.1016/j.revmed.2017.06.007. Epub 2017 Jul 6.
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[Hard nut to crack in diagnosis of pituitary hyperplasia secondary to primary hypothyroidism and reasons of misdiagnosis].[原发性甲状腺功能减退继发垂体增生的诊断难题及误诊原因]
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Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption.一名选择性左甲状腺素吸收不良患者中,与原发性甲状腺功能减退相关的类似大腺瘤的垂体增生。
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Cureus. 2023 May 29;15(5):e39655. doi: 10.7759/cureus.39655. eCollection 2023 May.
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Primary hypothyroidism in a child leads to pituitary hyperplasia: A case report and literature review.儿童原发性甲状腺功能减退症导致垂体增生:一例报告及文献综述
Medicine (Baltimore). 2018 Oct;97(42):e12703. doi: 10.1097/MD.0000000000012703.