Abdallah Fadle Wafa, Al Reesi Ali, Al-Shabibi Saud, Khamis Al-Badi Maryam
Department of Pediatric Endocrinology, National Diabetes and Endocrine Center, Royal Hospital, Muscat, Oman.
Department of Internal Medicine, Sohar Hospital, Sohar, Oman.
Case Rep Endocrinol. 2022 May 29;2022:3382612. doi: 10.1155/2022/3382612. eCollection 2022.
Pituitary hyperplasia secondary to primary hypothyroidism (PHPH) is uncommon in children and is reversible with thyroxine therapy. We report an Omani girl who presented at the age of 13 years and 6 months with profound primary hypothyroidism due to Hashimoto's thyroiditis and secondary pituitary hyperplasia and hyperprolactinemia. Pituitary magnetic resonance imaging confirmed the presence of pituitary hyperplasia which regressed during follow-up after the administration of thyroxine therapy. The diagnosis of PHPH is very important in both children and adults in order to avoid unnecessary brain surgery or medical treatment for a presumed pituitary mass or adenoma. To our knowledge, this patient represents the first case of an Omani child presenting with PHPH.
原发性甲状腺功能减退继发垂体增生（PHPH）在儿童中并不常见，且通过甲状腺素治疗可逆转。我们报告了一名13岁6个月的阿曼女孩，她因桥本甲状腺炎导致严重原发性甲状腺功能减退，并继发垂体增生和高催乳素血症。垂体磁共振成像证实存在垂体增生，在给予甲状腺素治疗后的随访期间增生消退。PHPH的诊断对儿童和成人都非常重要，以避免因假定的垂体肿块或腺瘤而进行不必要的脑部手术或药物治疗。据我们所知，该患者是首例出现PHPH的阿曼儿童。
