Robert Wood Johnson Foundation Clinical Scholars Program, University of Pennsylvania, Philadelphia, 19104, USA.
Am Heart J. 2011 Apr;161(4):705-11. doi: 10.1016/j.ahj.2011.01.011.
Racial disparities in survival after out-of-hospital cardiac arrest have been reported, but their causes remain uncertain. We sought to determine if hospital racial composition accounted for survival differences for patients hospitalized after cardiac arrest.
We evaluated hospitalizations of white and black Medicare beneficiaries (2000-2007) admitted from the emergency department to the intensive care unit with a diagnosis of cardiac arrest or ventricular fibrillation. We examined unadjusted survival rates and developed a multivariable logistic regression model that included patient and hospital factors.
We analyzed 68,115 cardiac arrest admissions. Unadjusted survival to hospital discharge was worse for blacks (n = 7,942) compared with whites (n = 60,173) (30% vs 33%, P < .001). In multivariate analyses accounting for patient and hospital factors, adjusted probability of survival was worse for black patients at hospitals with higher proportions of black patients (31%, 95% CI 29%-32%) compared with predominately white hospitals (46%, 95% CI 36%-57%; P = .003). Similarly, whites had worse risk-adjusted survival at hospitals with higher proportions of black patients (28%, 95% CI 27%-30%) compared with predominately white hospitals (32%, 95% CI 31%-33%, P = .006). Blacks were more likely to be admitted to hospitals with low survival rates (23% vs 15%, P < .001).
Hospitals with large black patient populations had worse cardiac arrest outcomes than predominantly white hospitals, and blacks were more likely to be admitted to these high-mortality hospitals. Understanding these differences in survival outcomes may uncover the causes for these disparities and lead to improved survival for all cardiac arrest victims.
据报道,院外心搏骤停后生存存在种族差异,但原因仍不确定。我们试图确定医院的种族构成是否解释了心搏骤停后住院患者的生存差异。
我们评估了 2000-2007 年从急诊室收入重症监护病房的白人及黑人医疗保险受益人的住院情况,诊断为心搏骤停或心室颤动。我们检查了未调整的生存率,并建立了一个包含患者和医院因素的多变量逻辑回归模型。
我们分析了 68115 例心搏骤停入院患者。未经调整的住院期间存活率黑人(n=7942)较白人(n=60173)差(30% vs 33%,P<.001)。在多变量分析中考虑到患者和医院因素,与以白人为主的医院(46%,95%CI 36%-57%;P=.003)相比,黑人患者在黑人患者比例较高的医院(31%,95%CI 29%-32%)的调整后存活概率更差。同样,与以白人为主的医院(32%,95%CI 31%-33%)相比,白人患者在黑人患者比例较高的医院(28%,95%CI 27%-30%)的风险调整后存活率更差(P=.006)。黑人更有可能被收入生存率较低的医院(23%比 15%,P<.001)。
黑人患者较多的医院心搏骤停结局较白人为主的医院差,黑人更有可能被收入这些高死亡率的医院。了解这些生存结果差异的原因可能会揭示这些差异的原因,并提高所有心搏骤停患者的生存率。