Department of Palliative Care, Policy and Rehabilitation, Cicely Saunders Institute, King's College London, Bessemer Road, Denmark Hill, London, UK.
J Clin Epidemiol. 2011 Aug;64(8):913-24. doi: 10.1016/j.jclinepi.2010.12.013. Epub 2011 Apr 6.
To examine the factor structure of the Missoula Vitas Quality of Life Index (MVQOLI) in palliative care patients in South Africa and Uganda and to assess the tool's appropriateness for measuring quality of life (QOL) in this context.
Cross-sectional survey using the MVQOLI, a 26-item QOL measure containing five subscales (Function, Symptoms, Interpersonal, Well being, and Transcendent), in five palliative care services in South Africa and Uganda.
Two hundred eighty-five patients were recruited; mean age was 40.1 years; 197 (69.1%) were female; primary diagnoses were human immunodeficiency virus infection (80.7%) and cancer (17.9%). A five-factor solution, accounting for 55% of variance, presented the best model of fit. The factors corresponded relatively closely to the original subscales, with only 4 of the 20 items not loading on the factor corresponding to the appropriate subscale. Internal consistency was high (α=0.83).
We found evidence of five factors underpinning the MVQOLI in a large sample of South African and Ugandan palliative care patients. The five factors corresponded reasonably well to the original subscales, suggesting that it is a promising measure for use in this population. However, further testing of its psychometric properties, comprehensibility, and scoring require further research in sub-Saharan Africa.
检验南非和乌干达姑息治疗患者中密苏里州生命质量指数（MVQOLI）的因子结构，并评估该工具在该背景下衡量生命质量（QOL）的适宜性。
使用 MVQOLI 进行横断面调查，MVQOLI 是一种包含五个分量表（功能、症状、人际关系、幸福感和超越）的 26 项 QOL 测量工具，在南非和乌干达的五个姑息治疗服务中进行。
共招募了 285 名患者；平均年龄为 40.1 岁；197 名（69.1%）为女性；主要诊断为人免疫缺陷病毒感染（80.7%）和癌症（17.9%）。占方差 55%的五因素解决方案呈现了最佳的拟合模型。这些因素与原始分量表相对接近，只有 20 项中的 4 项没有加载到与相应分量表对应的因子上。内部一致性较高（α=0.83）。
我们在南非和乌干达的大量姑息治疗患者中发现了支持 MVQOLI 的五个因素。这五个因素与原始分量表相当吻合，表明它是一种有前途的测量工具，可用于该人群。然而，需要进一步研究该工具在撒哈拉以南非洲的心理测量学特性、可理解性和评分。
