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1
Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis.饮食甲基缺乏、微小RNA表达与肝癌发生易感性
J Nutrigenet Nutrigenomics. 2010;3(4-6):259-66. doi: 10.1159/000324362. Epub 2011 Apr 6.
2
Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis.膳食甲基缺乏、微小RNA表达与肝癌发生易感性
World Rev Nutr Diet. 2010;101:123-130. doi: 10.1159/000314517. Epub 2010 Apr 30.
3
MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma.微小 RNA-500 作为肝细胞癌的潜在诊断标志物。
Biomarkers. 2009 Nov;14(7):529-38. doi: 10.3109/13547500903150771.
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Differential expression of microRNAs during hepatocarcinogenesis induced by methyl deficiency in rats.大鼠甲基缺乏诱导肝癌发生过程中微小RNA的差异表达
Nutr Rev. 2008 Aug;66 Suppl 1:S33-5. doi: 10.1111/j.1753-4887.2008.00064.x.
5
Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression.乙型肝炎病毒X蛋白通过白细胞介素-6激活微小RNA-21表达促进肝细胞癌转化。
Eur J Cancer. 2014 Oct;50(15):2560-9. doi: 10.1016/j.ejca.2014.07.008. Epub 2014 Jul 30.
6
Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice.微小RNA-155在C57BL/6小鼠胆碱缺乏和氨基酸限定饮食诱导的肝癌发生早期阶段的作用
Hepatology. 2009 Oct;50(4):1152-61. doi: 10.1002/hep.23100.
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[Real-time quantification of microRNAs in Huh7 cells by stem-loop reverse transcriptase polymerase chain reaction].[通过茎环逆转录聚合酶链反应对Huh7细胞中的微小RNA进行实时定量]
Zhonghua Gan Zang Bing Za Zhi. 2009 Aug;17(8):603-6.
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Further reduction in adenovirus vector-mediated liver transduction without largely affecting transgene expression in target organ by exploiting microrna-mediated regulation and the Cre-loxP recombination system.利用 microRNA 介导的调控和 Cre-loxP 重组系统，进一步减少腺病毒载体介导的肝脏转导，而在靶器官中对转基因表达的影响不大。
Mol Pharm. 2012 Dec 3;9(12):3452-63. doi: 10.1021/mp300248u. Epub 2012 Nov 12.
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Targeted anticancer effect through microRNA-181a regulated tumor-specific hTERT replacement.通过 microRNA-181a 调控的肿瘤特异性 hTERT 替换实现靶向抗癌作用。
Cancer Lett. 2015 Jan 28;356(2 Pt B):918-28. doi: 10.1016/j.canlet.2014.11.006. Epub 2014 Nov 8.
10
Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs.母体/父体饮食中叶酸和维生素 B12 失衡对全球甲基化和调控 miRNA 的影响。
Sci Rep. 2019 Nov 26;9(1):17602. doi: 10.1038/s41598-019-54070-9.

引用本文的文献

1
Deciphering the role of aberrant DNA methylation in NAFLD and NASH.解读异常DNA甲基化在非酒精性脂肪性肝病和非酒精性脂肪性肝炎中的作用。
Heliyon. 2022 Oct 18;8(10):e11119. doi: 10.1016/j.heliyon.2022.e11119. eCollection 2022 Oct.
2
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams.哺乳期母体甲基供体补充可预防高脂肪蔗糖摄入引起的母体高同型半胱氨酸血症。
Int J Mol Sci. 2013 Dec 16;14(12):24422-37. doi: 10.3390/ijms141224422.
3
Epigenetic events in liver cancer resulting from alcoholic liver disease.酒精性肝病导致的肝癌中的表观遗传事件。
Alcohol Res. 2013;35(1):57-67.
4
Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet.膳食补充甲基供体可减少肥胖症饮食喂养大鼠的脂肪肝，并改变脂肪酸合酶 DNA 甲基化谱。
Genes Nutr. 2013 Jan;8(1):105-13. doi: 10.1007/s12263-012-0300-z. Epub 2012 May 31.

本文引用的文献

1
MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality.微小RNA-221在肝细胞癌中靶向Bmf并与肿瘤多灶性相关。
Clin Cancer Res. 2009 Aug 15;15(16):5073-81. doi: 10.1158/1078-0432.CCR-09-0092. Epub 2009 Aug 11.
2
Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia.微小RNA的异常过表达通过下调自然杀伤细胞淋巴瘤/白血病中的肿瘤抑制因子激活AKT信号通路。
Blood. 2009 Oct 8;114(15):3265-75. doi: 10.1182/blood-2009-06-222794. Epub 2009 Jul 29.
3
Role of microRNA in anticancer drug resistance.微小RNA在抗癌药物耐药性中的作用。
Int J Cancer. 2010 Jan 1;126(1):2-10. doi: 10.1002/ijc.24782.
4
MicroRNAs in Cancer.癌症中的微小RNA
Annu Rev Med. 2009;60:167-79. doi: 10.1146/annurev.med.59.053006.104707.
5
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties.肝癌中miR-122表达缺失与肝脏表型的抑制及转移特性的获得相关。
Oncogene. 2009 Oct 8;28(40):3526-36. doi: 10.1038/onc.2009.211. Epub 2009 Jul 20.
6
MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia.参与肿瘤抑制和癌基因通路的微小RNA：对肝胆肿瘤的影响。
Hepatology. 2009 Aug;50(2):630-7. doi: 10.1002/hep.23010.
7
miR-15a and miR-16-1 in cancer: discovery, function and future perspectives.miR-15a 和 miR-16-1 在癌症中的作用、发现和未来展望。
Cell Death Differ. 2010 Feb;17(2):215-20. doi: 10.1038/cdd.2009.69. Epub 2009 Jun 5.
8
Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet.肝脏表观遗传表型预先决定了喂食致脂性甲基缺乏饮食的小鼠对肝脂肪变性的个体易感性。
J Hepatol. 2009 Jul;51(1):176-86. doi: 10.1016/j.jhep.2009.03.021. Epub 2009 May 3.
9
The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells.mir-34微小RNA对线虫体内和人乳腺癌细胞体外的DNA损伤反应是必需的。
Oncogene. 2009 Jun 25;28(25):2419-24. doi: 10.1038/onc.2009.106. Epub 2009 May 4.
10
A microRNA, miR-101a, controls mammary gland development by regulating cyclooxygenase-2 expression.一种微小RNA，即miR-101a，通过调控环氧化酶-2的表达来控制乳腺发育。
Differentiation. 2009 Feb;77(2):181-7. doi: 10.1016/j.diff.2008.10.001. Epub 2008 Nov 20.

Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis.

作者信息

Starlard-Davenport Athena, Tryndyak Volodymyr, Kosyk Oksana, Ross Sharon R, Rusyn Ivan, Beland Frederick A, Pogribny Igor P

机构信息

Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Arizona 72079, USA.

出版信息

J Nutrigenet Nutrigenomics. 2010;3(4-6):259-66. doi: 10.1159/000324362. Epub 2011 Apr 6.

DOI:10.1159/000324362
PMID:21474957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3085529/
Abstract
摘要