Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA.
AIDS Behav. 2012 Jan;16(1):139-50. doi: 10.1007/s10461-011-9941-y.
We studied 1163 sexually-active HIV-infected South African men and women in an urban primary care program to understand patterns of sexual behaviors and whether these behaviors differed by partner HIV status. Overall, 40% reported a HIV-positive partner and 60% a HIV-negative or status unknown partner; and 17.5% reported >2 sex acts in the last 2 weeks, 16.4% unprotected sex in the last 6 months, and 3.7% >1 sex partner in the last 6 months. Antiretroviral therapy (ART) was consistently associated with decreased sexual risk behaviors, as well as with reporting a HIV-negative or status unknown partner. The odds of sexual risk behaviors differed by sex; and were generally higher among participants reporting a HIV-positive partner, but continued among those with a HIV-negative or status unknown partner. These data support ART as a means of HIV prevention. Engaging in sexual risk behaviors primarily with HIV-positive partners was not widely practiced in this setting, emphasizing the need for couples-based prevention.
我们研究了在城市初级保健项目中 1163 名活跃的 HIV 感染者，以了解性行为模式，以及这些行为是否因伴侣 HIV 状况而异。总体而言，40%的人报告有 HIV 阳性伴侣，60%的人报告有 HIV 阴性或未知状况的伴侣；17.5%的人报告在过去 2 周内有超过 2 次性行为，16.4%的人在过去 6 个月内有无保护性行为，3.7%的人在过去 6 个月内有超过 1 个性伴侣。抗逆转录病毒疗法（ART）始终与降低性风险行为以及报告 HIV 阴性或未知状况的伴侣相关。性风险行为的几率因性别而异；在报告 HIV 阳性伴侣的参与者中通常更高，但在 HIV 阴性或未知状况的伴侣中仍在继续。这些数据支持将 ART 作为 HIV 预防的一种手段。在这种情况下，主要与 HIV 阳性伴侣发生性行为风险行为的情况并不普遍，这强调了需要基于伴侣的预防措施。
