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经吻合口置管减少了先天性十二指肠梗阻婴儿对中心静脉通路和肠外营养的需求。

Trans-anastomotic tubes reduce the need for central venous access and parenteral nutrition in infants with congenital duodenal obstruction.

作者信息

Hall N J, Drewett M, Wheeler R A, Griffiths D M, Kitteringham L J, Burge D M

机构信息

Wessex Regional Centre for Paediatric Surgery, Southampton University Hospitals NHS Trust, Mailpoint 44, Tremona Road, Southampton, SO16 6YD, UK.

出版信息

Pediatr Surg Int. 2011 Aug;27(8):851-5. doi: 10.1007/s00383-011-2896-2. Epub 2011 Apr 8.

Abstract

PURPOSE

To determine the effect of trans-anastomotic tube (TAT) feeding on outcome following repair of congenital duodenal obstruction (CDO).

METHODS

Retrospective comparative study of all infants with CDO over 10 years. Data are median (range). Mann-Whitney U test and Fisher's exact test were used.

RESULTS

Of 55 infants with CDO (48 atresia, 7 stenosis), 17 were managed with a TAT, 38 without. Enteral feeds were commenced earlier in infants with a TAT compared to those without (TAT 2 days post-repair [1-4] vs. no-TAT 3 days post-repair [1-7]; p = 0.006). Infants with a TAT achieved full enteral feeds significantly sooner than those without (TAT 6 days post-repair [2-12] vs. no-TAT 9 days post-repair [3-36]; p = 0.005). Significantly fewer infants in the TAT group required central venous catheter (CVC) placement and parenteral nutrition (PN) than in the no-TAT group (TAT 2/17 vs. no-TAT 28/38, p < 0.0001). There were six CVC-related complications (5 infections, 1 PN extravasation) and four TATs became displaced and were removed before achieving full enteral feeds. One infant with a TAT with trisomy 21 and undiagnosed Hirschsprung disease developed an anastomotic leak and jejunal perforation requiring re-operation.

CONCLUSIONS

A TAT significantly shortens time to full enteral feeds in infants with CDO significantly reducing the need for central venous access and PN.

摘要

目的

确定经吻合口管(TAT)喂养对先天性十二指肠梗阻(CDO)修复术后结局的影响。

方法

对10年间所有CDO婴儿进行回顾性比较研究。数据为中位数(范围)。采用曼-惠特尼U检验和费舍尔精确检验。

结果

55例CDO婴儿(48例闭锁,7例狭窄)中,17例采用TAT治疗,38例未采用。与未使用TAT的婴儿相比,使用TAT的婴儿肠内喂养开始时间更早(TAT组术后2天[1 - 4天],未使用TAT组术后3天[1 - 7天];p = 0.006)。使用TAT的婴儿比未使用TAT的婴儿显著更快实现完全肠内喂养(TAT组术后6天[2 - 12天],未使用TAT组术后9天[3 - 36天];p = 0.005)。TAT组需要放置中心静脉导管(CVC)和肠外营养(PN)的婴儿明显少于未使用TAT组(TAT组2/17,未使用TAT组28/38,p < 0.0001)。有6例CVC相关并发症(5例感染,1例PN外渗),4根TAT移位,在实现完全肠内喂养前被移除。1例患有21三体综合征且未诊断出先天性巨结肠病的使用TAT的婴儿发生吻合口漏和空肠穿孔,需要再次手术。

结论

TAT显著缩短了CDO婴儿实现完全肠内喂养所需的时间,显著减少了中心静脉通路和PN的需求。

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