Mikhasik S V, Fedotov V P, Leshchenko G M
Vestn Dermatol Venerol. 1990(7):45-8.
Mycologic examinations of patients with mycoses of the soles, working at 5 metallurgical plants in the town of Zaporozhye, have detected T. rubrum in 71.3 percent and T. interdigitale in 28.7 percent of cases. In 110 (18.3 percent) patients C. albicans were isolated from foci of involvement in parallel with Trichophyton. As a rule these patients were engaged in 'hot' shops and suffered from dysfunctions of various vital organs and from metabolic disorders. Mycoses of the soles complicated with Candida infection were characterized by marked exudation and dissemination with symptoms of eczema, intensive itching, efflorescence of the allergic type. High immediate and delayed-type hypersensitivity to administration of Candida antigen was observed in them. Cell-mediated and humoral immune response of these patients was essentially uncoordinated with depression of the T-immunity and nonspecific defense factors as a rule.
对扎波罗热市5家冶金厂患有足癣的工人进行真菌学检查发现，71.3%的病例中检出红色毛癣菌，28.7%的病例中检出指间毛癣菌。110例（18.3%）患者的感染灶中除毛癣菌外还分离出白色念珠菌。通常这些患者在“高温”车间工作，患有各种重要器官功能障碍和代谢紊乱。并发念珠菌感染的足癣表现为明显渗出和扩散，伴有湿疹症状、剧烈瘙痒、过敏型皮疹。对这些患者进行念珠菌抗原给药时，观察到高度的即刻和迟发型超敏反应。这些患者的细胞介导免疫和体液免疫反应通常基本不协调，T免疫和非特异性防御因子受到抑制。
