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早期乳腺癌的剂量强度:社区实践经验。

Dose intensity in early-stage breast cancer: a community practice experience.

机构信息

Fairfax Northern Virginia Hematology Oncology, Fairfax, VA.

出版信息

J Oncol Pract. 2009 Nov;5(6):287-90. doi: 10.1200/JOP.091036.

DOI:10.1200/JOP.091036
PMID:21479074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2869188/
Abstract

Although nodal status, grade, size, and receptor status play roles in determining breast cancer prognosis, there is increasing evidence that maintaining dose intensity of adjuvant chemotherapy increases disease-free survival rate.

摘要

虽然淋巴结状态、分级、大小和受体状态在确定乳腺癌预后方面起作用,但越来越多的证据表明维持辅助化疗的剂量强度可以提高无病生存率。

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本文引用的文献

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Undertreatment of cancer patients with chemotherapy is a global concern.癌症患者化疗治疗不足是一个全球关注的问题。
J Oncol Pract. 2008 May;4(3):114-5. doi: 10.1200/JOP.0831502.
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Risk and timing of neutropenic events in adult cancer patients receiving chemotherapy: the results of a prospective nationwide study of oncology practice.接受化疗的成年癌症患者中性粒细胞减少事件的风险及发生时间:一项全国肿瘤学实践前瞻性研究的结果
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Relative dose intensity: improving cancer treatment and outcomes.相对剂量强度:改善癌症治疗及预后
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5
Protocols for managing chemotherapy-induced neutropenia in clinical oncology practices.临床肿瘤学实践中化疗引起的中性粒细胞减少症的管理方案。
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30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study.可手术乳腺癌辅助性CMF随机研究的30年随访:队列研究
BMJ. 2005 Jan 29;330(7485):217. doi: 10.1136/bmj.38314.622095.8F. Epub 2005 Jan 13.
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Incidence and predictors of low dose-intensity in adjuvant breast cancer chemotherapy: a nationwide study of community practices.辅助性乳腺癌化疗中低剂量强度的发生率及预测因素:一项全国性社区实践研究。
J Clin Oncol. 2003 Dec 15;21(24):4524-31. doi: 10.1200/JCO.2003.05.002.
8
Delivering adjuvant chemotherapy to women with early-stage breast carcinoma: current patterns of care.为早期乳腺癌女性提供辅助化疗:当前的治疗模式
Cancer. 2001 Sep 15;92(6):1354-67. doi: 10.1002/1097-0142(20010915)92:6<1354::aid-cncr1458>3.0.co;2-p.
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Oncology (Williston Park). 2001 Oct;15(10):1296-306; discussion 1310-1, 1314.
10
Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up.辅助性环磷酰胺、甲氨蝶呤和氟尿嘧啶用于治疗淋巴结阳性乳腺癌:20年随访结果
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