Gill Ritu R
Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA.
Recent Results Cancer Res. 2011;189:27-43. doi: 10.1007/978-3-642-10862-4_3.
Malignant pleural mesothelioma (MPM) is an asbestos-related neoplasm that originates in pleural mesothelial cells and progresses locally along the pleura until it encases the lungs and mediastinum, ultimately causing death. Imaging plays a crucial role in diagnosis and optimal management. Computed tomography (CT) continues to be the primary and initial imaging modality. Magnetic resonance imaging (MRI) complements CT scan and is superior in determining chest wall and diaphragmatic invasion. FDG18-PET/CT provides anatamo-metabolic information and is superior to both CT and MRI in overall staging and monitoring response to therapy. This chapter will detail the imaging finding of MPM and role of imaging in guiding management.
恶性胸膜间皮瘤(MPM)是一种与石棉相关的肿瘤,起源于胸膜间皮细胞,沿胸膜局部进展,直至包裹肺和纵隔,最终导致死亡。影像学在诊断和最佳治疗管理中起着关键作用。计算机断层扫描(CT)仍然是主要的初始影像学检查方式。磁共振成像(MRI)可补充CT扫描,在确定胸壁和膈肌侵犯方面更具优势。18F-FDG-PET/CT提供解剖代谢信息,在总体分期和监测治疗反应方面优于CT和MRI。本章将详细介绍MPM的影像学表现以及影像学在指导治疗管理中的作用。