Mel'nychuk D O, Skoryk L V, Scholz C, Mitsyk E V, Guly M F
Ukr Biokhim Zh. 1977 Sep-Oct;49(5):86-93.
A rise in the level of carbonic acid in animal blood at practically unchanged pH causes an increase in the value of free [NAD+]/[NADH] and [NADP+]/[NADPH] ratios in the liver cells cytoplasm. The increase in the oxidizing power of the liver cells cytoplasm is observed against a background of a rise in both the total level of keto-acids in blood and concentration of pyruvate oxaloacetate and alpha-ketoglutarate in the liver and kidneys of animals. The level of lactate, glutamate and citrate in these tissues also grows. The level of ketonic bodies in blood of the animals with a higher concentration of carbonic acid is somewhat lower than that in the animals with a lower concentration of HCO3 and CO2 in blood.
在动物血液中碳酸水平升高而pH值几乎不变的情况下，会导致肝细胞细胞质中游离的[NAD⁺]/[NADH]和[NADP⁺]/[NADPH]比值升高。在动物血液中酮酸总水平升高以及肝脏和肾脏中丙酮酸、草酰乙酸和α-酮戊二酸浓度升高的背景下，观察到肝细胞细胞质氧化能力增强。这些组织中乳酸、谷氨酸和柠檬酸水平也升高。碳酸浓度较高的动物血液中酮体水平略低于血液中HCO₃和CO₂浓度较低的动物。
