Horton Heather K, Silverstein Steven M
School of Social Welfare, University at Albany, New York, NY 12222, USA.
Cogn Neuropsychiatry. 2011 May;16(3):256-83. doi: 10.1080/13546805.2010.538231. Epub 2011 Apr 8.
There has been a relative lack of research on deaf people with schizophrenia, and no data exist regarding symptom structure in this population. Thus, we determined the factor structure of the 24-item Brief Psychiatric Rating Scale (BPRS) in deaf (n = 34) and hearing (n = 31) people with schizophrenia and compared it to a standard four-factor solution.
An obliquely rotated factor analysis produced a solution for the BPRS that resembled others in the literature. Symptom clusters were additionally compared to cognitive and social-cognitive abilities.
Activity and disorganised symptoms were the most consistent correlates of visual- and thought and language-related skills for deaf and hearing subjects respectively. Affective symptoms and facial affect processing were positively correlated among deaf but not hearing subjects.
The data suggest that current symptom models of schizophrenia are valid in both hearing and deaf patients. However, relations between symptoms, cognition, and outcome from the general (hearing) literature cannot be generalised to deaf patients. Findings are broadly consistent with pathophysiologic models of schizophrenia suggesting a fundamental cortical processing algorithm operating across several domains of neural activity including vision, and thought and language. Support is provided for recent advances in social-cognitive interventions for people with schizophrenia.
对患有精神分裂症的聋人的研究相对较少,且尚无关于该人群症状结构的数据。因此,我们确定了24项简明精神病评定量表(BPRS)在聋人(n = 34)和听力正常(n = 31)的精神分裂症患者中的因子结构,并将其与标准的四因子解决方案进行比较。
进行斜交旋转因子分析得出了BPRS的一个解决方案,该方案与文献中的其他方案相似。此外,还将症状集群与认知和社会认知能力进行了比较。
活动症状和紊乱症状分别是聋人和听力正常受试者视觉、思维及语言相关技能最一致的相关因素。情感症状与面部表情加工在聋人受试者中呈正相关,而在听力正常受试者中则不然。
数据表明,目前精神分裂症的症状模型在听力正常和聋人患者中均有效。然而,来自一般(听力正常)文献的症状、认知与结果之间的关系不能推广到聋人患者。研究结果与精神分裂症的病理生理模型大致一致,表明一种基本的皮质加工算法在包括视觉、思维和语言在内的多个神经活动领域起作用。为精神分裂症患者社会认知干预的最新进展提供了支持。