Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Neuron. 2011 Apr 14;70(1):3-5. doi: 10.1016/j.neuron.2011.03.015.
Hippocampal pyramidal cells can be divided into place cells, which fire action potentials when an animal is in specific locations, and silent cells, which are not spatially selective. In this issue of Neuron, Epsztein et al. find intracellular differences between place and silent cells by using whole-cell recordings in freely moving rats.
海马锥体神经元可以分为位置细胞和沉默细胞,当动物处于特定位置时,位置细胞会产生动作电位,而沉默细胞则没有空间选择性。在本期《神经元》杂志上,Epsztein 等人通过在自由活动的大鼠中进行全细胞记录,发现了位置细胞和沉默细胞之间的细胞内差异。