Hassanin N, Gabal M A
Department of Nutrition and Food Chemistry, Ain-Shams University, Arab Republic of Egypt.
Vet Hum Toxicol. 1990 Dec;32(6):536-40.
Metabolites of fusarium moniliforme isolates from different types of corn were characterized biologically and chemically. The biological assays included rat feeding, rat dermal tests and inoculation of embryonated eggs. Thin-layer chromatography, gas liquid chromatography, and mass spectrophotometry were used to isolate and determine their chemical identities. The metabolites were identified as diacetoxyscripenol, ipomeanol, ipomeanine and diplodiatoxin. The biological tests revealed significant weight loss in rats fed the contaminated corn for 5 w. Hemorrhages and edema in the brain and intestine were detected in all the groups of rats.
对从不同类型玉米中分离出的串珠镰刀菌的代谢产物进行了生物学和化学特性分析。生物学试验包括大鼠喂养、大鼠皮肤试验和鸡胚接种。采用薄层色谱法、气相色谱法和质谱法分离并确定其化学特性。这些代谢产物被鉴定为二乙酰氧基司替泊醇、甘薯酮、甘薯宁和双孢盘菌素。生物学试验显示，喂食受污染玉米5周的大鼠体重显著减轻。在所有大鼠组中均检测到大脑和肠道出血及水肿。
