一种无标记荧光开启酶扩增测定法，用于使用配体响应的 G-四链体形成进行 DNA 检测。
A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation.
机构信息
Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
出版信息
Chem Commun (Camb). 2011 May 21;47(19):5461-3. doi: 10.1039/c1cc11396h. Epub 2011 Apr 11.
PMID:21483972
Abstract
A facile and general label-free assay for sensitive and selective DNA detection has been developed based on enzyme amplification and ligand-responsive quadruplex formation.
摘要
基于酶扩增和配体响应的四链体形成，开发了一种简便通用的无标记检测方法，用于灵敏和选择性的 DNA 检测。
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