Physical Medicine and Rehabilitation, VA Central California Health Care System, Fresno, CA, USA.
Curr Rheumatol Rep. 2011 Jun;13(3):251-6. doi: 10.1007/s11926-011-0177-7.
Not all fractures heal well. One method that has been used to improve fracture healing is low-intensity pulsed ultrasound (LIPUS). LIPUS has been US Food and Drug Administration approved for several years, and some preclinical and clinical evidence indicates that fracture healing can be improved by this technique, which appears to be generally safe. There are several suggested mechanisms of action of LIPUS. Clinical studies generally support its usefulness in accelerating fracture healing. A less-established modality is whole body vibration (WBV), which appears to stimulate bone and muscle growth while suppressing adipogenesis in animal studies. Early studies in humans, including some in children with disabilities, suggest that WBV holds promise as a technique for reducing fracture risk. The exact place of WBV in preventing fracture remains to be established.
并非所有骨折都能愈合良好。一种旨在改善骨折愈合的方法是低强度脉冲超声（LIPUS）。LIPUS 已获得美国食品和药物管理局多年的批准，一些临床前和临床证据表明，这种技术可以改善骨折愈合，而且通常是安全的。LIPUS 有几种作用机制。临床研究普遍支持其在加速骨折愈合方面的有效性。全身振动（WBV）是一种不太成熟的方法，在动物研究中，它似乎可以刺激骨骼和肌肉生长，同时抑制脂肪生成。在人类中的早期研究，包括一些残疾儿童的研究，表明 WBV 有望成为一种降低骨折风险的技术。WBV 在预防骨折中的确切作用仍有待确定。
