Wei Biao Fang, Ge Xiang Hua
Department of Orthopaedic Surgery, Linyi People's Hospital, Linyi - P.R. China.
Hip Int. 2011 Mar-Apr;21(2):206-10. doi: 10.5301/HIP.2011.6525. Epub 2011 Apr 6.
Osteonecrosis of the femoral head (ONFH) is a disorder that can lead to femoral head collapse. Various procedures have been advocated to avert the need for total hip replacement. These include vascularised and non-vascularised bone grafting procedures. We examined the effect of core decompression combined with an allogeneic, antigen-extracted, autolysed fibular allograft and autologous impacted bone grafting for the treatment of osteonecrosis of the femoral head. The study included 162 patients (223 hips; 61 females, 101 males; mean age 33.5 years, range 19-54 years) with stage II-III avascular necrosis of the femoral head according to the ARCO (Association Research Circulation Osseous) classification. The outcome was determined by changes in the Harris hip score, by progression in radiographic stages, and by the need for hip replacement. The mean follow-up was 24 months (range 7- 42 months). Statistical evaluation included Kaplan-Meier survival analysis. The mean Harris hip score increased from 61 to 85. Excellent and good results were obtained in 93.3% of cases in stage II, and 87% in stages III with a survivorship of 81% in all cases. Core decompression combined with an allogeneic, antigen-extracted, autolysed fibular allograft and autologous impacted bone grafting may be the treatment of choice, particularly in the precollapse stage.
股骨头坏死(ONFH)是一种可导致股骨头塌陷的病症。人们提倡采用各种手术来避免全髋关节置换的必要性。这些手术包括带血管蒂和不带血管蒂的骨移植手术。我们研究了髓芯减压联合同种异体、抗原提取、自溶腓骨移植和自体打压植骨治疗股骨头坏死的效果。该研究纳入了162例患者(223髋;女性61例,男性101例;平均年龄33.5岁,范围19 - 54岁),根据ARCO(骨循环研究协会)分类,这些患者为II - III期股骨头缺血性坏死。通过Harris髋关节评分的变化、影像学分期的进展以及髋关节置换的需求来确定治疗结果。平均随访时间为24个月(范围7 - 42个月)。统计评估包括Kaplan - Meier生存分析。Harris髋关节评分的平均值从61分提高到了85分。II期病例中93.3%获得了优和良的结果,III期病例中这一比例为87%,所有病例的生存率为81%。髓芯减压联合同种异体、抗原提取、自溶腓骨移植和自体打压植骨可能是首选的治疗方法,尤其是在塌陷前期。