Department of Orthopaedics, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, 610041, People's Republic of China.
J Orthop Surg Res. 2020 Mar 24;15(1):116. doi: 10.1186/s13018-020-1565-3.
The aim of this study was to determine mid-and-long term follow-up results of patients with early femoral head osteonecrosis who were treated by modified free vascularized fibular grafting combined with core decompression and bone grafting.
Forty-four patients at early ONFH were included in this study. Visual analog scale (VAS) pain scores, range of hip motion (ROM), and Harris hip score (HHS) were recorded to assess the clinical outcome; Western Ontario McMaster Osteoarthritis index (WOMAC) scores and Short Form 36 health survey (SF-36) were conducted to measure the living quality; X-ray film or magnetic resonance imaging (MRI) was used to evaluate radiographic progression; survivorship was defined as patients did not undergo the total hip arthroplasty (THA) or fusion at the last follow-up. Median follow-up was 7.4 years (6-8.2 years).
The mean VAS score, ROM, and HHS were significantly improved at the final follow-up compared with preoperative values (p < 0.001). Health assessment including WOMAC scores and SF-36 were also better than those preoperatively (p < 0.001). Seven patients progressed to Ficat III and the four patients progressed to Ficat IV with osteoarthritis. Eight patients who cannot tolerate the pain and had poor living quality underwent THA.
Modified non-vascularized allogeneic fibula Grafting combined with core decompression and bone grafting could improve the clinical outcomes and enhance the quality of life for patients with early ONFH.
本研究旨在探讨改良游离腓骨移植联合髓芯减压植骨术治疗早期股骨头坏死患者的中期和长期随访结果。
本研究纳入 44 例早期股骨头坏死患者。通过视觉模拟评分(VAS)疼痛评分、髋关节活动范围(ROM)和 Harris 髋关节评分(HHS)评估临床疗效;采用西部安大略省和麦克马斯特大学骨关节炎指数(WOMAC)评分和简明健康调查量表 36 项(SF-36)评估生活质量;X 线片或磁共振成像(MRI)评估影像学进展;采用生存分析定义末次随访时未行全髋关节置换术(THA)或融合术的患者。中位随访时间为 7.4 年(6-8.2 年)。
与术前相比,末次随访时 VAS 评分、ROM 和 HHS 均显著改善(p<0.001)。WOMAC 评分和 SF-36 等健康评估也优于术前(p<0.001)。7 例进展为 Ficat III 期,4 例进展为 Ficat IV 期伴骨关节炎。8 例因疼痛不能耐受和生活质量差而行 THA。
改良非血管化同种异体腓骨移植联合髓芯减压植骨术可改善早期股骨头坏死患者的临床疗效,提高生活质量。