[细菌中程序性细胞死亡的最新研究]
[Recent research on programmed cell death in bacteria].
作者信息
Wu Jiang, Deng Lei, Fan Xinjian
机构信息
Infectious Disease Center, West China Hospital, Sichuan University, Chengdu 610041, China.
出版信息
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Feb;28(1):199-202.
Similar to multicellular animals, single-cell organisms, such as bacteria show the phenomenon of programmed cell death (PCD). The PCD not only can play an important role in various physiological procedures, but also can eliminate bacteria with irreversible injuries. The PCD of single cell in a colony is for the benefits of other bacteria in the same colony to achieve the development and reproduction of the whole colony. Disturbing or destroying such PCD may provide a new way for antibiotic drug research and development.
与多细胞动物类似，单细胞生物，如细菌，也表现出程序性细胞死亡（PCD）现象。PCD不仅在各种生理过程中发挥重要作用，还能清除受到不可逆损伤的细菌。菌落中单个细胞的PCD是为了同一菌落中的其他细菌受益，以实现整个菌落的发育和繁殖。干扰或破坏这种PCD可能为抗生素药物研发提供新途径。
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