Citrino G, Check J H, Bollendorf A, Hourani W, Diantonio A
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, NJ, USA.
Clin Exp Obstet Gynecol. 2011;38(1):21-3.
To determine the percentage of males with a low hypoosmotic swelling (HOS) test score in couples having in vitro fertilization-embryo transfer (IVF-ET) where the male partner had normal motile densities and no antisperm antibodies.
The results were also analyzed according to the percentage of HOS scores < 50% when morphology using strict criteria was < or = 4% or > 4%. A retrospective review was performed.
There were 250 subnormal HOS scores out of 1993 otherwise normal semen specimens.
12.5% of couples would have had conventional oocyte inseminations rather than ICSI if the HOS test had not been not performed (it is rarely performed by other IVF centers). Without ICSI expected live delivered pregnancy rates would be close to zero for males with low HOS tests < 50%. Intracytoplasmic sperm injection allows pregnancy rates almost as good as completely normal sperm.
在男性伴侣精子活动密度正常且无抗精子抗体的体外受精-胚胎移植（IVF-ET）夫妇中，确定低渗肿胀（HOS）试验评分低的男性所占的比例。
当采用严格标准的形态学<或=4%或>4%时，还根据HOS评分<50%的百分比对结果进行了分析。进行了一项回顾性研究。
在1993份其他方面正常的精液标本中，有250份HOS评分低于正常。
如果未进行HOS试验（其他IVF中心很少进行），12.5%的夫妇本会进行传统的卵母细胞授精而非卵胞浆内单精子注射（ICSI）。对于HOS试验<50%的男性，若不进行ICSI，预期的活产妊娠率将接近零。卵胞浆内单精子注射使妊娠率几乎与完全正常精子的情况一样好。
